Description

4-(n-(4-Fluoro-3-Methoxyphenyl)Sulfamoyl)Phenylboronic Acid is a high-purity, advanced pharmaceutical intermediate and building block. This compound is valued for its role as a key synthon in modern synthetic chemistry, particularly in cross-coupling reactions like the Suzuki-Miyaura reaction. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials industries for the synthesis of novel active compounds.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of active pharmaceutical ingredients (APIs), especially those containing sulfonamide and biaryl motifs.
• Suzuki-Miyaura Cross-Coupling: Serves as a versatile boronic acid reagent for forming carbon-carbon bonds in the development of complex organic molecules.
• Agrochemical Research: Used in the discovery and synthesis of new herbicides, fungicides, and insecticides.
• Material Science: A precursor for creating functionalized polymers and organic electronic materials.
• Chemical Biology & Proteomics: Employed in the design and synthesis of molecular probes and enzyme inhibitors for biological studies.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs for the production of bespoke compounds for client projects.

Basic Information

Product Name	4-(n-(4-Fluoro-3-Methoxyphenyl)Sulfamoyl)Phenylboronic Acid
CAS No.	957120-99-9
Molecular Formula	C19H17BFNO5S
Molecular Weight	409.22 g/mol
Synonyms	4-[[(4-Fluoro-3-methoxyphenyl)sulfamoyl]phenyl]boronic acid; [4-[[(4-Fluoro-3-methoxyphenyl)sulfamoyl]phenyl]boronic acid; 4-(N-(4-Fluoro-3-methoxyphenyl)sulfamoyl)benzeneboronic acid; B-[4-[[(4-Fluoro-3-methoxyphenyl)amino]sulfonyl]phenyl]boronic acid; 4-Fluoro-3-methoxy-N-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]benzenesulfonamide (pinacol ester precursor)
EINECS	Contact for details

Quality Control

Our 4-(n-(4-Fluoro-3-Methoxyphenyl)Sulfamoyl)Phenylboronic Acid is manufactured under strict quality systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high purity and consistent identity. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is light-sensitive (store away from light). Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Assay	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.