Description

3-Bromo-2-Chloro-5-(Trifluoromethyl)Phenylboronic Acid is a high-purity, multi-functional boronic acid derivative essential for modern synthetic chemistry. This compound serves as a critical building block in cross-coupling reactions, enabling the efficient construction of complex molecular architectures. It is primarily utilized by research institutions and industrial R&D departments in the pharmaceutical, agrochemical, and advanced materials sectors for developing novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel drug candidates, particularly in oncology and CNS therapeutic areas.
• Agrochemical Synthesis: Used to create advanced active ingredients for crop protection products, including herbicides and fungicides with enhanced efficacy.
• Material Science Research: Employed in the development of organic electronic materials, such as OLEDs and semiconductors, due to its halogenated and fluorinated structure.
• Chemical Biology Probes: Serves as a building block for creating bioconjugates and molecular probes used in diagnostic and imaging applications.
• Catalyst Ligand Development: Utilized in the synthesis of specialized ligands for transition metal catalysis.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis houses serving the fine chemical and life science industries.

Basic Information

Product Name	3-Bromo-2-Chloro-5-(Trifluoromethyl)Phenylboronic Acid
CAS No.	957120-85-3
Molecular Formula	C7H4BBrClF3O2
Molecular Weight	303.27 g/mol
Synonyms	(3-Bromo-2-chloro-5-(trifluoromethyl)phenyl)boronic acid; 3-Bromo-2-chloro-5-(trifluoromethyl)benzeneboronic acid; B-[3-Bromo-2-chloro-5-(trifluoromethyl)phenyl]boronic acid; 2-Chloro-3-bromo-5-(trifluoromethyl)phenylboronic acid; 957120-85-3; Boronic acid, B-[3-bromo-2-chloro-5-(trifluoromethyl)phenyl]-; AKOS005258208
EINECS	Contact for details

Quality Control

Our 3-Bromo-2-Chloro-5-(Trifluoromethyl)Phenylboronic Acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure high purity and batch-to-batch consistency suitable for sensitive coupling reactions. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.