Description

3-Borono-5-Bromo-2-Fluorobenzoic Acid is a high-purity, multi-functional aromatic building block designed for advanced synthetic chemistry. This compound is valued for its unique combination of reactive handles—boronic acid, bromo, and fluoro substituents—enabling precise cross-coupling and further functionalization. It is essential for researchers and manufacturers in pharmaceutical development and agrochemical synthesis who require reliable, high-quality intermediates for creating complex molecules.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for Suzuki-Miyaura cross-coupling reactions to form biaryl structures.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides that require halogenated and boronated aromatic cores.
• Material Science Research: Serves as a building block for creating organic electronic materials, such as ligands for OLEDs or molecular sensors.
• Chemical Biology & Proteomics: Employed in the design and synthesis of chemical probes and bioconjugation reagents targeting specific proteins or enzymes.
• Custom Synthesis & Contract Manufacturing: An ideal starting material for custom synthesis projects requiring selective, sequential functionalization on a benzoic acid scaffold.

Basic Information

Product Name	3-Borono-5-Bromo-2-Fluorobenzoic Acid
CAS No.	957120-63-7
Molecular Formula	C7H5BBrFO4
Molecular Weight	261.83 g/mol
Synonyms	5-Bromo-2-fluoro-3-boronobenzoic acid; 3-Borono-5-bromo-2-fluorobenzoic acid; Benzoic acid, 3-borono-5-bromo-2-fluoro-; 5-Bromo-2-fluoro-3-carboxyphenylboronic acid; [3-Bromo-5-(carboxy)-2-fluorophenyl]boronic acid; 957120-63-7; BRN 9081025
EINECS	Contact for details

Quality Control

Every batch of 3-Borono-5-Bromo-2-Fluorobenzoic Acid is produced and tested under strict quality management protocols to ensure consistency and reliability for your critical applications. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing purity, identity, and impurity profiles. Our quality systems are designed to support cGMP and ISO standards for pharmaceutical and fine chemical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when possible to prevent oxidation and hydrolysis of the boronic acid moiety. Keep away from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥97.0%
Water Content (KF)	≤1.0%
Heavy Metals	≤20 ppm
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.