Description

5-Borono-4-Chloro-2-Fluorobenzoic Acid is a high-purity, multi-functional boronic acid derivative serving as a critical building block in advanced organic synthesis. Its unique halogenated and boronic acid functional groups make it an indispensable reagent for constructing complex molecular architectures, particularly in pharmaceutical research and development. This compound is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing biaryl compounds, a core structure in many active pharmaceutical ingredients (APIs).
• Agrochemical Synthesis: Used in the development of novel herbicides and fungicides, leveraging its halogen and boronic acid groups for structural diversity.
• Material Science Research: Building block for creating organic electronic materials, metal-organic frameworks (MOFs), and advanced polymers.
• Chemical Biology & Proteomics: Serves as a versatile handle for bioconjugation and the development of enzyme inhibitors or molecular probes.
• Catalyst Ligand Synthesis: Used to prepare sophisticated ligands for transition metal catalysis in asymmetric synthesis.
• Custom Synthesis & Contract Manufacturing: Essential for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) producing bespoke compounds for client projects.

Basic Information

Product Name	5-Borono-4-Chloro-2-Fluorobenzoic Acid
CAS No.	957066-06-7
Molecular Formula	C7H4BClFO4
Molecular Weight	217.37 g/mol
Synonyms	4-Chloro-2-fluoro-5-boronobenzoic acid; 5-Borono-4-chloro-2-fluorobenzoic acid; (4-Chloro-2-fluoro-5-carboxyphenyl)boronic acid; Benzoic acid, 5-borono-4-chloro-2-fluoro-; 957066-06-7; 4-Chloro-2-fluoro-5-carboxybenzeneboronic acid; 2-Fluoro-4-chloro-5-boronobenzoic acid
EINECS	Contact for details

Quality Control

Our production of 5-Borono-4-Chloro-2-Fluorobenzoic Acid adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Each lot is analyzed using advanced techniques including HPLC, NMR, and elemental analysis. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.