Description

2-Bromo-5-(Trifluoromethyl)Phenylboronic Acid is a high-purity, synthetically valuable boronic acid derivative. This compound serves as a critical building block in modern organic synthesis, particularly in cross-coupling reactions like the Suzuki-Miyaura reaction, enabling the efficient construction of complex biaryl structures. It is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require precise and reliable intermediates for developing new active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, especially those containing trifluoromethyl and bromo substituents for enhanced bioavailability and metabolic stability.
• Agrochemical Synthesis: Used in creating novel herbicides, fungicides, and insecticides where the unique phenylboronic acid scaffold introduces specific biological activity.
• Material Science Research: Building block for the development of organic electronic materials, liquid crystals, and metal-organic frameworks (MOFs) due to its functional handles for further derivatization.
• Suzuki-Miyaura Cross-Coupling Reactions: A versatile reagent for forming carbon-carbon bonds between aryl halides and boronic acids, a cornerstone methodology in medicinal and process chemistry.
• Chemical Biology & Proteomics: Can be utilized in the synthesis of molecular probes and inhibitors for studying enzyme function and protein interactions.
• Custom Synthesis & Contract Manufacturing: Supplied to fine chemical companies for use in custom synthesis projects and scale-up production under cGMP conditions.

Basic Information

Product Name	2-Bromo-5-(Trifluoromethyl)Phenylboronic Acid
CAS No.	957034-38-7
Molecular Formula	C7H5BBrF3O2
Molecular Weight	267.83 g/mol
Synonyms	[2-Bromo-5-(trifluoromethyl)phenyl]boronic acid; (2-Bromo-5-(trifluoromethyl)phenyl)boronic acid; 2-Bromo-5-trifluoromethylbenzeneboronic acid; 2-Bromo-alpha,alpha,α-trifluoro-m-tolylboronic acid; Boronic acid, B-[2-bromo-5-(trifluoromethyl)phenyl]-; 957034-38-7; 2-Bromo-5-(trifluoromethyl)benzeneboronic Acid
EINECS	Contact for details

Quality Control

Our 2-Bromo-5-(Trifluoromethyl)Phenylboronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure high purity and consistency. Certificates of Analysis (COA) with detailed specifications are provided for every shipment, supporting traceability and compliance for research and cGMP manufacturing applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥97.0%
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.