Description

Valnivudine is a synthetic nucleoside analogue with significant antiviral research applications. This compound is of high interest for its potential role in the development of novel therapeutic agents targeting viral infections. It is primarily utilized by pharmaceutical R&D laboratories, academic research institutions, and biotechnology companies engaged in antiviral drug discovery and development programs.

Application

• Antiviral Research & Development: Serves as a key intermediate or active pharmaceutical ingredient (API) in the synthesis and study of new antiviral medications.
• Biochemical Assays: Used as a reference standard or probe in enzymatic studies and mechanism-of-action research for viral polymerases.
• Pharmaceutical Synthesis: Acts as a critical building block in the multi-step synthesis of more complex nucleoside-based drug candidates.
• Academic & Preclinical Studies: Employed in university and institutional labs for in vitro and in vivo studies to evaluate efficacy, toxicity, and pharmacokinetic profiles.

Basic Information

Product Name	Valnivudine
CAS No.	956483-03-7
Molecular Formula	C11H15N3O5S
Molecular Weight	301.32 g/mol
Synonyms	1-((2S,4R,5R)-4-Hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-5-methyl-2,4(1H,3H)-pyrimidinedione 3'-O-ethyldithiocarbonate; 3'-O-Ethyloxythiocarbonyl-5-methyluridine; 3'-O-Ethoxythiocarbonylthymidine; NSC 760372; Valnivudin; 5-Methyl-3'-O-ethoxythiocarbonyluridine
EINECS	Contact for details

Quality Control

Our Valnivudine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the stringent requirements for research-grade materials. Certificates of Analysis (COA) detailing all specifications are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.