Description

Nelfinavir Mesylates CAS NO 15989-65-8 is the mesylate salt form of nelfinavir, a potent and selective inhibitor of the HIV-1 protease enzyme. This active pharmaceutical ingredient (API) is critical for the formulation of antiretroviral medications used in combination therapy for the treatment of Human Immunodeficiency Virus (HIV) infection. It is primarily required by pharmaceutical manufacturers and research institutions engaged in the development and production of antiviral therapeutics.

Application

• Pharmaceutical API: Primary use as the active ingredient in the manufacture of antiretroviral drugs for HIV/AIDS treatment.
• Combination Therapy Formulations: Used in fixed-dose combination tablets or capsules alongside other antiretroviral agents.
• Clinical Research: Serves as a reference standard and key material in preclinical and clinical studies for new HIV treatment regimens.
• Generic Drug Manufacturing: Essential for companies producing generic versions of protease inhibitor medications.
• Drug Discovery & Development: Used as a biochemical tool and lead compound in antiviral research programs.

Basic Information

Product Name	Nelfinavir Mesylates
CAS No.	15989-65-8
Molecular Formula	C32H45N3O4S • CH4O3S
Molecular Weight	663.88 g/mol
Synonyms	Nelfinavir Mesylate; AG1343 Mesylate; Viracept (brand name mesylate salt); [3S-[2(2S*,3S*),3α,4aβ,8aβ]]-N-(1,1-Dimethylethyl)decahydro-2-[2-hydroxy-3-[(3-hydroxy-2-methylbenzoyl)amino]-4-(phenylthio)butyl]-3-isoquinolinecarboxamide Monomethanesulfonate; (3S,4aS,8aS)-N-tert-Butyl-2-[(2R,3R)-2-hydroxy-3-[(3-hydroxy-2-methylbenzoyl)amino]-4-(phenylsulfanyl)butyl]decahydro-3-isoquinolinecarboxamide methanesulfonate
EINECS	Contact for details

Quality Control

Our Nelfinavir Mesylates is manufactured under strict quality systems. Each batch undergoes comprehensive analytical testing to ensure it meets high-purity standards suitable for pharmaceutical use. We provide full traceability and support regulatory filings with comprehensive documentation. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is available for every batch upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be kept under conditions that minimize exposure to atmospheric humidity to maintain stability and potency.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference standard
Identification (HPLC)	Retention time corresponds to reference
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity: ≤ 0.5% Total impurities: ≤ 2.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.