Description

[3,4-Diacetyloxy-5-(5-Oxo-2,4,9-Triazabicyclo[4.3.0]Nona-3,7,10-Trien-9-Yl)Oxolan-2-Yl]Methyl Acetate is a high-purity, advanced pharmaceutical intermediate with a complex bicyclic heterocyclic structure. This compound is critical for the synthesis of novel nucleoside analogs and antiviral agents, offering researchers and manufacturers a reliable building block for complex molecular construction. It is primarily utilized by pharmaceutical R&D teams and fine chemical producers focused on developing next-generation therapeutics.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel antiviral and anticancer nucleoside analogs.
• Antiviral Drug Research: Serves as a core scaffold for the development of new therapeutic agents targeting viral polymerases.
• Medicinal Chemistry: Used in structure-activity relationship (SAR) studies and lead optimization for new chemical entities.
• Bioconjugation & Prodrug Development: The acetyl-protected groups and reactive sites make it suitable for prodrug strategies and targeted delivery systems.
• Fine Chemical Synthesis: Employed in multi-step organic synthesis for constructing complex heterocyclic frameworks.
• Biochemical Research: Used as a substrate or inhibitor in enzymatic studies related to nucleotide metabolism.

Basic Information

Item	Details
Product Name	[3,4-Diacetyloxy-5-(5-Oxo-2,4,9-Triazabicyclo[4.3.0]Nona-3,7,10-Trien-9-Yl)Oxolan-2-Yl]Methyl Acetate
CAS No.	16754-78-2
Molecular Formula	C16H18N4O8
Molecular Weight	394.34 g/mol
Synonyms	1-(5-O-[(Acetyloxy)methyl]-2,3-di-O-acetyl-β-D-ribofuranosyl)-1,2,4-triazole-3-carboxamide; 1-(2,3,5-Tri-O-acetyl-β-D-ribofuranosyl)-1,2,4-triazole-3-carboxamide; Ribavirin 2',3',5'-Triacetate; Ribavirin Triacetate; 1-β-D-Ribofuranosyl-1,2,4-triazole-3-carboxamide 2',3',5'-triacetate; 3-Carbamoyl-1-β-D-ribofuranosyl-1,2,4-triazole 2',3',5'-triacetate; Virazole Triacetate
EINECS	Contact for details

Quality Control

Our [3,4-Diacetyloxy-5-(5-Oxo-2,4,9-Triazabicyclo[4.3.0]Nona-3,7,10-Trien-9-Yl)Oxolan-2-Yl]Methyl Acetate is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Production adheres to cGMP guidelines where applicable, and each lot is supported by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We ensure compliance with ICH guidelines for residual solvents and heavy metals, making it suitable for advanced pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Related Substances (HPLC)	Total impurities ≤2.0% Any single impurity ≤0.5%
Water Content (KF)	≤0.5%
Residual Solvents (GC)	Complies with ICH Q3C
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.