Description

1-Adamantanamine Fumarate is a high-purity pharmaceutical intermediate and organic building block, specifically the fumarate salt of 1-adamantanamine (amantadine). This compound is valued for its enhanced stability and solubility profile compared to the free base, making it a critical component in advanced synthetic pathways. It is primarily utilized by research institutions and pharmaceutical manufacturers developing antiviral agents and neurological therapeutics.

Application

• Pharmaceutical Intermediate: Key starting material or salt form in the synthesis of antiviral drugs, including derivatives targeting influenza A and other viruses.
• Neurological Research: Used in the development and production of agents for Parkinson's disease and other central nervous system disorders.
• Organic Synthesis: Serves as a versatile, rigid building block in medicinal chemistry for creating novel molecular architectures with adamantane cores.
• Reference Standard: Employed as an analytical standard in quality control laboratories for method development and validation.
• Chemical Biology: Utilized in proteomics and biochemical research to study protein interactions and enzyme inhibition.

Basic Information

Product Name	1-Adamantanamine Fumarate
CAS No.	18720-83-7
Molecular Formula	C10H17N • C4H4O4
Molecular Weight	291.34 g/mol
Synonyms	Amantadine Fumarate; 1-Aminoadamantane Fumarate; Adamantan-1-amine Fumarate; Tricyclo[3.3.1.13,7]decan-1-amine Fumarate; 1-Adamantylamine Fumarate Salt; Adamantane-1-amine Fumarate; Fumaric Acid Adamantan-1-amine Salt; PK-Merz (salt form)
EINECS	Contact for details

Quality Control

Our 1-Adamantanamine Fumarate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, identity confirmation by IR and NMR spectroscopy, and stringent control of residual solvents and heavy metals. Certificates of Analysis (COA) detailing all specifications are provided to ensure traceability and compliance with your research or cGMP-grade requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). The material is hygroscopic (moisture-sensitive) and should be handled under dry conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥98.0%
Loss on Drying	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm
Related Substances (HPLC)	Total impurities ≤2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.