Description

Famotine Hydrochloride CAS NO 10500-82-0 is a pharmaceutical-grade active pharmaceutical ingredient (API) belonging to the class of histamine H2-receptor antagonists. This compound is critical for the development and formulation of therapeutic agents targeting gastric acid secretion. It is primarily required by pharmaceutical manufacturers and research institutions engaged in the development of gastrointestinal treatments and related clinical studies.

Application

• Pharmaceutical API: Primary active ingredient in the formulation of anti-ulcer and gastroprotective medications.
• Clinical Research: Used as a reference standard and investigational compound in pharmacological studies related to histamine receptor activity.
• Drug Development: Serves as a key intermediate in the synthesis and process development of new H2-antagonist drug candidates.
• Analytical Standard: High-purity material for use in quality control laboratories for method development, validation, and calibration (HPLC, GC, etc.).
• Biochemical Research: Tool compound for studying the mechanism of action of H2-receptor antagonists in vitro and in vivo.

Basic Information

Product Name	Famotine Hydrochloride
CAS No.	10500-82-0
Molecular Formula	C11H15N3O2S • HCl
Molecular Weight	289.78 g/mol
Synonyms	Famotidine Hydrochloride; Famotidinum Hydrochloridum; 3-[[[2-[(Aminoiminomethyl)amino]-4-thiazolyl]methyl]thio]-N-(aminosulfonyl)propanimidamide Hydrochloride; MK-208 Hydrochloride; YM-11170; Gaster; Pepcid; Gastropen; Ulfamid; Pepcidine; L-643,441
EINECS	Contact for details

Quality Control

Our Famotine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure it meets high-purity standards suitable for pharmaceutical applications. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with specifications for identity, purity, and impurities. We adhere to cGMP principles where applicable to ensure supply reliability and batch-to-batch consistency for our global B2B clients.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a dry environment to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.