Description

1-(2-Fluorobenzyl)-1H-Pyrazolo[3,4-B]Pyridine-3-Carboxylic Acid is a high-purity, advanced pharmaceutical intermediate with the CAS number 956011-26-0. This compound is a critical building block in modern medicinal chemistry, valued for its role in synthesizing novel active pharmaceutical ingredients (APIs) with targeted therapeutic effects. It is primarily required by research institutions and pharmaceutical manufacturers engaged in the development of new drug candidates, particularly in oncology and central nervous system (CNS) therapeutic areas.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the research and development of novel small-molecule drug candidates.
• Kinase Inhibitor Synthesis: Used in the construction of pyrazolopyridine-based scaffolds, which are prominent in the design of protein kinase inhibitors for cancer therapy.
• Medicinal Chemistry Research: Serves as a versatile building block for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• API Development: Integral to the synthetic route of Active Pharmaceutical Ingredients (APIs) targeting specific disease pathways.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations providing custom synthesis and process development services for the pharmaceutical industry.
• Academic Research: Utilized in university and institutional labs for exploratory research in heterocyclic chemistry and bioorganic chemistry.

Basic Information

Product Name	1-(2-Fluorobenzyl)-1H-Pyrazolo[3,4-B]Pyridine-3-Carboxylic Acid
CAS No.	956011-26-0
Molecular Formula	C15H10FN3O2
Molecular Weight	283.26 g/mol
Synonyms	1-[(2-Fluorophenyl)methyl]-1H-pyrazolo[3,4-b]pyridine-3-carboxylic acid; 1H-Pyrazolo[3,4-b]pyridine-3-carboxylic acid, 1-[(2-fluorophenyl)methyl]-; 956011-26-0; 1-(2-Fluorobenzyl)-1H-pyrazolo[3,4-b]pyridine-3-carboxylic acid; UNII-6F1Q2J7M8R; 6F1Q2J7M8R; 1-(2-Fluorobenzyl)-1H-pyrazolo[3,4-b]pyridin-3-carboxylic acid
EINECS	Contact for details

Quality Control

Our 1-(2-Fluorobenzyl)-1H-Pyrazolo[3,4-B]Pyridine-3-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, IR, MS), to ensure it meets the high standards required for pharmaceutical research and development. Certificates of Analysis (COA) detailing batch-specific results are provided and available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.