Description

2-(4-Fluorophenyl)-5,5-Dimethyl-1,3-Dioxane-2-Butanoic Acid is a specialized organic compound featuring a fluorinated aromatic ring and a dioxane-protected butanoic acid moiety, making it a valuable synthetic intermediate. This compound is engineered to provide a stable, protected carboxylic acid functionality for advanced multi-step organic synthesis, particularly in pharmaceutical research and development. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced material sectors for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), especially those requiring a fluorophenyl group for enhanced bioactivity and metabolic stability.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides where the fluorine atom and protected acid group are critical for efficacy.
• Material Science Research: Serves as a monomer or precursor for synthesizing specialized polymers and advanced organic materials with tailored properties.
• Chemical Biology Probes: Employed in the development of molecular probes and diagnostic agents due to its modifiable functional groups.
• Academic & Contract Research: Utilized in university laboratories and CROs (Contract Research Organizations) for methodological studies and the discovery of new chemical entities.
• Custom Synthesis & Scale-up: A critical starting material for custom synthesis projects, from milligram-scale discovery to kilogram-scale process development.

Basic Information

Product Name	2-(4-Fluorophenyl)-5,5-Dimethyl-1,3-Dioxane-2-Butanoic Acid
CAS No.	953805-21-5
Molecular Formula	C₁₆H₂₁FO₄
Molecular Weight	296.34 g/mol
Synonyms	4-(2-(4-Fluorophenyl)-5,5-dimethyl-1,3-dioxan-2-yl)butanoic acid; 2-(4-Fluorophenyl)-5,5-dimethyl-1,3-dioxane-2-butanoic acid; 4-[2-(4-Fluorophenyl)-5,5-dimethyl-1,3-dioxan-2-yl]butanoic acid; Butanoic acid, 4-[2-(4-fluorophenyl)-5,5-dimethyl-1,3-dioxan-2-yl]-; 953805-21-5; 4-(2-(4-Fluorophenyl)-5,5-dimethyl-1,3-dioxan-2-yl)butyric acid
EINECS	Contact for details

Quality Control

Our 2-(4-Fluorophenyl)-5,5-Dimethyl-1,3-Dioxane-2-Butanoic Acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment ensures the material meets the stringent requirements for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong acids and organic solvents. The container should be kept tightly sealed in a dry environment to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.