Description

3,4-Dihydroxybenzoic Acid 3-o-β-D-Glucuronide is a specialized glucuronide conjugate of protocatechuic acid, a key phenolic metabolite. This compound is of significant interest in pharmaceutical and nutraceutical research due to its role as a major phase II metabolite, influencing bioavailability and biological activity studies. It is primarily utilized by research institutions and manufacturers in the pharmaceutical, analytical, and life science sectors for applications in drug metabolism, pharmacokinetic research, and as a reference standard.

Application

• Pharmaceutical Reference Standard: Used as a high-purity certified standard for analytical method development and validation in drug metabolism and pharmacokinetic (DMPK) studies.
• Metabolite Research: A critical tool for investigating the metabolic pathways, bioavailability, and excretion profiles of polyphenolic compounds and related drugs.
• Biochemical Assay Development: Serves as a substrate or control in enzymatic assays, particularly those involving glucuronidation by UDP-glucuronosyltransferases (UGTs).
• Nutraceutical & Cosmetic Research: Employed in studies evaluating the stability, absorption, and efficacy of bioactive phenolic ingredients in supplements and topical formulations.
• Academic & Contract Research: Essential for basic and applied research in universities and CROs focusing on pharmacology, toxicology, and natural product chemistry.

Basic Information

Product Name	3,4-Dihydroxybenzoic Acid 3-o-β-D-Glucuronide
CAS No.	953037-17-7
Molecular Formula	C13H14O10
Molecular Weight	330.24 g/mol
Synonyms	Protocatechuic Acid 3-O-β-D-Glucuronide; 3-O-(β-D-Glucopyranosyluronic acid)protocatechuic acid; 4,5-Dihydroxybenzoic Acid 3-O-β-D-Glucuronide; PCA 3-O-Glucuronide; 3-β-D-Glucuronosyloxy-4,5-dihydroxybenzoic acid
EINECS	Contact for details

Quality Control

Our 3,4-Dihydroxybenzoic Acid 3-o-β-D-Glucuronide is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the stringent requirements for research and reference standard applications. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting batch-specific results.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; prolonged exposure to humidity or light should be avoided to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.