Description

Methyl2,5-Difluoro-3-Methylbenzoate CAS NO 952479-99-1 is a high-purity fluorinated aromatic ester building block essential for advanced organic synthesis. This compound is valued for its role in introducing specific fluorine-substituted benzoate motifs into complex molecular architectures, enabling precise tuning of physical and chemical properties. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for the creation of novel active ingredients and specialty materials.

Application

• Pharmaceutical Intermediate: A key synthon in the development of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and metabolic diseases.
• Agrochemical Synthesis: Used in the research and production of next-generation herbicides and fungicides, where the difluoro-methylbenzoate moiety can enhance bioavailability and environmental stability.
• Liquid Crystal & OLED Material Precursor: Serves as a starting material for synthesizing fluorinated aromatic cores used in electronic display technologies and organic light-emitting diodes (OLEDs).
• Polymer Modification: Incorporated as a monomer or modifier to impart specific solubility, thermal, or optical properties to high-performance engineering plastics and coatings.
• Chemical Research & Development: Employed in academic and industrial labs for method development, catalysis studies, and exploring new reactions involving fluorinated arenes.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of bespoke compounds and scaled-up processes.

Basic Information

Product Name	Methyl2,5-Difluoro-3-Methylbenzoate
CAS No.	952479-99-1
Molecular Formula	C9H8F2O2
Molecular Weight	186.16 g/mol
Synonyms	Methyl 2,5-difluoro-3-methylbenzoate; Benzoic acid, 2,5-difluoro-3-methyl-, methyl ester; 3-Methyl-2,5-difluorobenzoic acid methyl ester; Methyl 3-methyl-2,5-difluorobenzoate; 2,5-Difluoro-3-methylbenzoic acid methyl ester
EINECS	Contact for details

Quality Control

Our Methyl2,5-Difluoro-3-Methylbenzoate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment supports compliance with cGMP, ISO, and REACH standards for global supply.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed in a dry environment to minimize moisture exposure.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.