Description

5-Fluoro-3-Methyl-2-Nitro-Benzoic Acid is a high-purity, multi-functional aromatic carboxylic acid derivative, serving as a critical building block in advanced organic synthesis. Its unique trifunctional structure, incorporating fluorine, nitro, and carboxylic acid groups, makes it an indispensable intermediate for creating complex molecules with tailored properties. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules requiring a fluorinated aromatic core.
• Agrochemical Synthesis: Building block for developing new herbicides, fungicides, and pesticides, where the fluorine atom enhances biological activity and metabolic stability.
• Material Science Research: Used in the development of advanced polymers, liquid crystals, and organic electronic materials due to its electron-withdrawing nitro and carboxylic acid groups.
• Dye and Pigment Manufacturing: Intermediate for producing specialized azo dyes and pigments where the methyl and nitro groups influence color and fastness properties.
• Chemical Biology & Proteomics: Serves as a versatile scaffold for creating chemical probes, enzyme inhibitors, and bioconjugation reagents in life science research.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for bespoke synthesis projects requiring high-purity, complex intermediates.

Basic Information

Product Name	5-Fluoro-3-Methyl-2-Nitro-Benzoic Acid
CAS No.	952479-96-8
Molecular Formula	C8H6FNO4
Molecular Weight	199.14 g/mol
Synonyms	2-Nitro-5-fluoro-3-methylbenzoic acid; 3-Methyl-5-fluoro-2-nitrobenzoic acid; 5-Fluoro-3-methyl-2-nitrobenzoic acid; Benzoic acid, 5-fluoro-3-methyl-2-nitro-; 952479-96-8; 5-F-3-M-2-NO2-BA
EINECS	Contact for details

Quality Control

Every batch of 5-Fluoro-3-Methyl-2-Nitro-Benzoic Acid is manufactured under a strict quality management system and undergoes comprehensive analytical testing to ensure it meets the highest standards of purity and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, which includes data from HPLC, NMR, and other relevant spectroscopic methods. Our quality commitment aligns with cGMP principles where applicable, ensuring reliability for critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation. Keep away from incompatible materials such as strong bases and strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.