Description

(5-Chloro-4-Fluoro-2-Methoxyphenyl) Boronic Acid is a high-purity, functionalized boronic acid derivative that serves as a critical building block in modern synthetic chemistry. Its value lies in its unique halogenated and methoxylated aromatic structure, which enables precise cross-coupling reactions essential for constructing complex molecules. This compound is primarily needed by research institutions and pharmaceutical companies engaged in the development of active pharmaceutical ingredients (APIs), agrochemicals, and advanced materials.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel drug candidates, particularly in oncology and central nervous system (CNS) therapeutic areas.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides and fungicides, leveraging its halogenated phenyl ring for bioactivity.
• Material Science Research: Employed in the development of organic electronic materials, such as OLEDs and semiconductors, where its structure aids in tuning electronic properties.
• Chemical Biology Probes: Serves as a versatile handle for bioconjugation and the creation of molecular probes for diagnostic and research applications.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects requiring specific boronic acid derivatives.

Basic Information

Product Name	(5-Chloro-4-Fluoro-2-Methoxyphenyl) Boronic Acid
CAS No.	949892-09-5
Molecular Formula	C7H7BClFO3
Molecular Weight	203.39 g/mol
Synonyms	5-Chloro-4-fluoro-2-methoxybenzeneboronic acid; (5-Chloro-4-fluoro-2-methoxyphenyl)boronic acid; 2-Methoxy-5-chloro-4-fluorophenylboronic acid; Boronic acid, B-(5-chloro-4-fluoro-2-methoxyphenyl)-; 949892-09-5; AKOS005258155; FT-0773293
EINECS	Contact for details

Quality Control

Our (5-Chloro-4-Fluoro-2-Methoxyphenyl) Boronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure compliance with high-grade research and development standards. Comprehensive Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants or storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.