Description

2-Methyl-5-Trifluoromethyl-Phenylboronic Acid is a high-value organoboron building block essential for modern synthetic chemistry. Its core value lies in enabling the efficient construction of complex molecular architectures through versatile cross-coupling reactions. This compound is critically needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials industries for creating novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel drug candidates, particularly those requiring trifluoromethylated biaryl motifs.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides where the trifluoromethyl group enhances biological activity and metabolic stability.
• Ligand & Catalyst Development: Serves as a building block for creating specialized ligands and organometallic catalysts used in asymmetric synthesis.
• Material Science Research: Employed in the synthesis of organic electronic materials, such as OLED (Organic Light-Emitting Diode) emitters and charge-transport molecules.
• Chemical Biology Probes: Facilitates the creation of labeled compounds and molecular probes for studying biological pathways and target engagement.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of bespoke compounds on a commercial scale.

Basic Information

Product Name	2-Methyl-5-Trifluoromethyl-Phenylboronic Acid
CAS No.	947533-96-2
Molecular Formula	C8H8BF3O2
Molecular Weight	203.96 g/mol
Synonyms	(2-Methyl-5-(trifluoromethyl)phenyl)boronic acid; 2-Methyl-5-(trifluoromethyl)benzeneboronic acid; 5-Trifluoromethyl-2-methylphenylboronic acid; 2-Methyl-α,α,α-trifluoro-m-tolueneboronic acid; Boronic acid, B-[2-methyl-5-(trifluoromethyl)phenyl]-; 2-Methyl-5-trifluoromethylbenzeneboronic Acid
EINECS	Contact for details

Quality Control

Our 2-Methyl-5-Trifluoromethyl-Phenylboronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and process chemistry. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (argon or nitrogen) after opening to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.