Description

4-Methyl-3-Trifluoromethyl-Phenylboronic Acid is a high-value organoboron building block essential for modern synthetic chemistry. Its core value lies in enabling the efficient construction of complex molecules through versatile cross-coupling reactions, such as the Suzuki-Miyaura reaction. This compound is critically needed by R&D and production teams in the pharmaceutical, agrochemical, and advanced materials industries for developing novel active ingredients and functional compounds.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates containing trifluoromethyl and aryl motifs.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides that require specific fluorinated aromatic structures.
• Material Science: Serves as a precursor for creating functional polymers, liquid crystals, and organic electronic materials.
• Cross-Coupling Reactions: Primarily employed in palladium-catalyzed Suzuki-Miyaura couplings to form biaryl and complex aromatic systems.
• Chemical Research & Development: A versatile reagent in academic and industrial R&D labs for exploring new synthetic pathways and novel compound libraries.
• Fine Chemical Production: Integral to the multi-step synthesis of complex, high-value specialty chemicals.

Basic Information

Product Name	4-Methyl-3-Trifluoromethyl-Phenylboronic Acid
CAS No.	947533-94-0
Molecular Formula	C8H8BF3O2
Molecular Weight	203.96 g/mol
Synonyms	(4-Methyl-3-(trifluoromethyl)phenyl)boronic acid; 3-Trifluoromethyl-4-methylbenzeneboronic acid; 4-Methyl-3-trifluoromethylbenzeneboronic acid; Boronic acid, B-[4-methyl-3-(trifluoromethyl)phenyl]-; 947533-94-0; 4-Methyl-α,α,α-trifluoro-m-tolueneboronic acid
EINECS	Contact for details

Quality Control

Our 4-Methyl-3-Trifluoromethyl-Phenylboronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and titration methods, to ensure high purity and consistency. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available for every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.