Description

2-tert-Amyl-6-(Diphenylphosphino)Pyridine, Alpyphos is a specialized, sterically hindered phosphine-pyridine hybrid ligand designed for advanced catalytic applications. This compound matters for its ability to form highly active and selective transition metal complexes, particularly in challenging cross-coupling and hydrogenation reactions. It is primarily needed by R&D chemists and process engineers in the pharmaceutical, agrochemical, and fine chemical industries for developing novel synthetic routes and optimizing production processes.

Application

• Homogeneous Catalysis: As a key ligand for palladium, nickel, and other transition metals in cross-coupling reactions (e.g., Suzuki-Miyaura, Buchwald-Hartwig amination).
• Pharmaceutical Intermediate Synthesis: Enabling the efficient and selective construction of complex molecular scaffolds for active pharmaceutical ingredients (APIs).
• Asymmetric Hydrogenation: Facilitating the production of chiral intermediates with high enantiomeric purity for specialty chemicals.
• Material Science Research: Used in the development of novel organometallic complexes and catalysts for polymer synthesis.
• Agrochemical Manufacturing: Applied in the synthesis of advanced, high-performance crop protection agents.
• Academic & Industrial R&D: A valuable tool for exploring new catalytic methodologies and reaction mechanisms.

Basic Information

Product Name	2-tert-Amyl-6-(Diphenylphosphino)Pyridine, Alpyphos
CAS No.	947315-18-6
Molecular Formula	C22H24NP
Molecular Weight	333.41 g/mol
Synonyms	Alpyphos; 6-(Diphenylphosphino)-2-(1,1-dimethylpropyl)pyridine; 2-(tert-Pentyl)-6-(diphenylphosphino)pyridine; 2-(1,1-Dimethylpropyl)-6-(diphenylphosphino)pyridine; 2-tert-Pentyl-6-(diphenylphosphino)pyridine; Phosphine-Pyridine Ligand; P,N-Ligand
EINECS	Contact for details

Quality Control

Every batch of 2-tert-Amyl-6-(Diphenylphosphino)Pyridine is manufactured under strict quality management protocols. Our products undergo rigorous quality testing, including NMR, HPLC, and elemental analysis, to ensure compliance with high-purity standards for research and industrial use. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at room temperature (15-25°C) in a cool, dry, and well-ventilated area. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.