Description

n-[3,5-Bis(Trifluoromethyl)Phenyl]-N'-(9R)-Cinchonan-9-Yl-Urea CAS NO 945985-98-8 is a high-purity, chiral urea derivative designed for advanced chemical synthesis and research. This compound is valued for its role as a sophisticated organocatalyst and chiral auxiliary, enabling the development of enantiomerically pure pharmaceuticals and fine chemicals. It is essential for R&D laboratories and production facilities in the pharmaceutical, agrochemical, and specialty chemical sectors seeking to introduce molecular complexity with high stereoselectivity.

Application

• Asymmetric Organocatalysis: Employed as a chiral catalyst in enantioselective C-C and C-N bond-forming reactions.
• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of active pharmaceutical ingredients (APIs) with defined stereochemistry.
• Chiral Resolution Agent: Used to separate enantiomers of racemic mixtures in analytical and preparative chromatography.
• Ligand for Metal Complexes: Acts as a precursor for chiral ligands in transition metal catalysis.
• Agrochemical Research: Applied in the development of novel, enantiomerically pure herbicides and pesticides.
• Academic & Industrial R&D: A valuable tool for methodological development in synthetic organic chemistry and process optimization.

Basic Information

Item	Detail
Product Name	n-[3,5-Bis(Trifluoromethyl)Phenyl]-N'-(9R)-Cinchonan-9-Yl-Urea
CAS No.	945985-98-8
Molecular Formula	C29H24F6N4O
Molecular Weight	558.52 g/mol
Synonyms	(9R)-N-[3,5-Bis(trifluoromethyl)phenyl]-N'-[(9R)-cinchonan-9-yl]urea; Cinchona Alkaloid Urea Derivative; (R)-Cinchonidine Urea Derivative; (9R)-9-({[3,5-Bis(trifluoromethyl)phenyl]carbamoyl}amino)cinchonan; Organocatalyst 945985-98-8; Chiral Bifunctional Urea Catalyst; (R)-C9-Urea Catalyst; 945985-98-8
EINECS	Contact for details

Quality Control

Our n-[3,5-Bis(Trifluoromethyl)Phenyl]-N'-(9R)-Cinchonan-9-Yl-Urea is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and chiral analysis to confirm enantiomeric excess. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.