Description

Bis[2-(Di-T-Butylphosphino)Ethyl]Amine, Min. 97% is a high-purity, sterically hindered PN3-type pincer ligand, a critical component in homogeneous catalysis. Its primary value lies in its ability to form exceptionally stable and active metal complexes, particularly with late transition metals like palladium and nickel, enabling challenging cross-coupling and hydrogenation reactions. This ligand is essential for researchers and process chemists in the pharmaceutical, agrochemical, and fine chemical industries who require highly selective and efficient catalytic systems for complex organic synthesis.

Application

• Homogeneous Catalysis: As a key ligand for constructing highly active and selective palladium and nickel catalysts.
• Cross-Coupling Reactions: Enabling Buchwald-Hartwig amination, Suzuki-Miyaura, and Negishi couplings under mild conditions with high turnover numbers.
• Hydrogenation & Reduction: Facilitating the selective hydrogenation of challenging substrates, including nitriles and imines.
• Pharmaceutical Intermediate Synthesis: Critical for constructing complex molecular architectures in API (Active Pharmaceutical Ingredient) development.
• Agrochemical Synthesis: Used in the production of advanced, high-performance crop protection agents.
• Material Science & Polymerization: Serving as a ligand in catalytic systems for the synthesis of specialty polymers and functional materials.
• Academic & Industrial R&D: A fundamental tool for developing new catalytic methodologies and exploring reaction mechanisms.

Basic Information

Product Name	Bis[2-(Di-T-Butylphosphino)Ethyl]Amine, Min. 97%
CAS No.	944710-34-3
Molecular Formula	C22H49NP2
Molecular Weight	389.58 g/mol
Synonyms	PN3 Pincer Ligand; N,N-Bis[2-(di-tert-butylphosphanyl)ethyl]amine; Diethylamine, 2,2'-(phosphinylidynedi-4,1-phenylene)bis[ N,N-bis(1,1-dimethylethyl)-; 2,2'-(Phosphinylidynedi-4,1-phenylene)bis[N,N-bis(1,1-dimethylethyl)diethylamine]; (PtBu2CH2CH2)2NH; N,N-Bis[2-(di-tert-butylphosphino)ethyl]amine; DTBPEN Ligand
EINECS	Contact for details

Quality Control

Our Bis[2-(Di-T-Butylphosphino)Ethyl]Amine is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity. Each lot undergoes rigorous analytical testing, including NMR (1H, 13C, 31P) for structural confirmation and HPLC for purity assessment. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (argon or nitrogen) at 2-8°C to minimize oxidation and ensure long-term stability. Allow the container to reach room temperature in a dry environment before opening to prevent moisture condensation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (NMR)	Conforms to structure
Purity (HPLC)	Min. 97.0%
31P NMR Purity	Min. 97.0%
Solubility	Soluble in common organic solvents (THF, Toluene, DCM)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.