Description

(S)-Bethanechol CAS NO 944538-50-5 is the single enantiomer form of the cholinergic agonist bethanechol, offering superior specificity and potency for research and development applications. This high-purity chiral compound is critical for studying muscarinic acetylcholine receptor subtypes and their physiological roles. It is primarily utilized by pharmaceutical researchers, contract development and manufacturing organizations (CDMOs), and academic institutions focused on neuropharmacology and urology.

Application

• Pharmaceutical Intermediate: Key starting material or reference standard in the synthesis of novel muscarinic receptor-targeting therapeutics.
• Biochemical Research: Tool compound for in vitro and ex vivo studies of parasympathetic nervous system activation, smooth muscle contraction, and glandular secretion.
• Mechanism of Action Studies: Used to investigate receptor selectivity, signal transduction pathways, and the effects of cholinergic stimulation in various tissue models.
• Analytical Reference Standard: Serves as a high-purity calibrant in HPLC, LC-MS, and other analytical methods for quality control and method development.
• Academic & Preclinical Development: Employed in university and institutional labs for fundamental research into autonomic nervous system function and related disorders.

Basic Information

Product Name	(S)-Bethanechol
CAS No.	944538-50-5
Molecular Formula	C7H17N2O2+
Molecular Weight	161.23 g/mol (free base)
Synonyms	(S)-Bethanechol; (S)-2-[(Aminocarbonyl)oxy]-N,N,N-trimethyl-1-propanaminium; (S)-Carbamoylcholine; (S)-Urecholine; L-Bethanechol; Bethanechol (S)-enantiomer; (S)-Carbachol (common misnomer); (2S)-2-[(Aminocarbonyl)oxy]-N,N,N-trimethylpropan-1-aminium
EINECS	Contact for details

Quality Control

Our (S)-Bethanechol is manufactured under strict quality management systems. Each batch is subjected to comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets exacting standards for research and development use. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming identity, purity, and enantiomeric excess.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept in a desiccated environment to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥98.0%
Enantiomeric Purity (Chiral HPLC)	≥99.0%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.