Description

Huperzine CAS NO 116-28-9 is a potent, naturally occurring alkaloid derived from the Chinese club moss *Huperzia serrata*. This compound is highly valued for its selective and reversible inhibition of acetylcholinesterase, a key enzyme in the nervous system. It is primarily sought after by manufacturers in the pharmaceutical, nutraceutical, and research sectors for the development of cognitive support supplements and therapeutic agents targeting neurological conditions.

Application

• Pharmaceutical Intermediates: Serves as a critical active pharmaceutical ingredient (API) or precursor in formulations for cognitive enhancement and neuroprotective drugs.
• Dietary Supplements & Nootropics: A key component in high-quality nutraceutical products aimed at supporting memory, focus, and overall cognitive function.
• Neurological Research: Used extensively in biochemical and pharmacological research as a reference standard and tool compound for studying cholinergic systems and neurodegenerative disease models.
• Cosmeceuticals: Incorporated into advanced skincare formulations for its potential neuroprotective and anti-inflammatory properties.
• Veterinary Medicine: Applied in veterinary cognitive support supplements for aging companion animals.

Basic Information

Product Name	Huperzine
CAS No.	116-28-9
Molecular Formula	C15H18N2O
Molecular Weight	242.32 g/mol
Synonyms	Huperzine A; Selagine; (-)-Huperzine A; (5R,9R,11E)-5-Amino-11-ethylidene-5,6,9,10-tetrahydro-7-methyl-5,9-methanocycloocta[b]pyridin-2(1H)-one; L-Huperzine A; Neurotrophic agent; ZT-1 (prodrug derivative); HupA
EINECS	Contact for details

Quality Control

Our Huperzine is produced under strict quality management systems to ensure batch-to-batch consistency and high purity. We offer grades suitable for research, nutraceutical, and pharmaceutical applications. All batches are accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant industry standards, and our quality systems support compliance with cGMP, ISO, and other regulatory frameworks as required.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from incompatible materials and sources of ignition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference standard
Identification (HPLC)	Retention time matches reference
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Specific Rotation	-150° to -165° (c=1, MeOH)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.