Description

n-Methylcarbamylcholine is a synthetic cholinergic agent and a stable carbamate analog of acetylcholine. This compound is of significant interest in biochemical and pharmacological research due to its role as a potent and selective agonist for muscarinic acetylcholine receptors. It serves as a critical tool for scientists and manufacturers in the pharmaceutical and life sciences sectors, enabling advanced studies in neurochemistry, receptor characterization, and drug discovery.

Application

• Pharmacological Research: A key tool compound for studying muscarinic acetylcholine receptor (mAChR) function, subtype selectivity, and signaling pathways.
• Neurochemical Studies: Used in vitro and ex vivo to investigate cholinergic neurotransmission, synaptic plasticity, and cognitive function models.
• Drug Discovery & Development: Serves as a reference standard and active pharmaceutical ingredient (API) intermediate in the development of novel therapeutics for neurological disorders.
• Biochemical Assays: Employed in high-throughput screening (HTS) and functional assays to identify and characterize new receptor modulators.
• Academic Research: Essential for university and institutional labs focused on neuroscience, molecular pharmacology, and cellular signaling.
• Diagnostic Agent Development: Investigated for potential use in developing diagnostic tools for conditions related to cholinergic system dysfunction.

Basic Information

Product Name	n-Methylcarbamylcholine
CAS No.	14721-69-8
Molecular Formula	C9H21N2O2+
Molecular Weight	189.28 g/mol (cation)
Synonyms	Methylcarbamylcholine; McN-A-343; (4-Hydroxyphenyl)trimethylammonium methylcarbamate; 4-Hydroxy-N,N,N-trimethylbenzenaminium methylcarbamate; 4-[[(Dimethylamino)carbonyl]oxy]-N,N,N-trimethylbenzenaminium; NSC 113986; mAChR agonist McN-A-343
EINECS	Contact for details

Quality Control

We supply n-Methylcarbamylcholine in high-purity grades suitable for research and development. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) are available upon request, detailing parameters such as purity (by HPLC), identity confirmation, and impurity profiles to support your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.