Description

Atropine Sulfate is a high-purity, crystalline salt of the tropane alkaloid atropine, widely recognized for its anticholinergic and antimuscarinic pharmacological activity. This compound is critical for its role as a pre-anesthetic agent to inhibit salivation and bronchial secretions, as well as an antidote for organophosphate and carbamate poisoning. It serves as an essential active pharmaceutical ingredient (API) and a key biochemical reagent for manufacturers in the pharmaceutical, research, and diagnostic sectors globally.

Application

• Pharmaceutical Manufacturing: Primary use as an Active Pharmaceutical Ingredient (API) in injectable formulations, ophthalmic solutions, and tablets.
• Medical Antidote: Critical component in emergency kits and auto-injectors for the treatment of nerve agent and organophosphate pesticide poisoning.
• Pre-anesthetic Medication: Used to reduce respiratory tract secretions before surgery.
• Ophthalmic Procedures: Employed to induce mydriasis (pupil dilation) and cycloplegia (paralysis of accommodation) for eye examinations and surgery.
• Bradycardia Treatment: Used to increase heart rate in specific clinical conditions of symptomatic bradycardia.
• Biochemical Research: Serves as a standard and tool compound in pharmacological studies targeting muscarinic acetylcholine receptors.
• Veterinary Medicine: Used in veterinary practices for similar therapeutic applications as in human medicine.

Basic Information

Product Name	Atropine Sulfate
CAS No.	55-48-1
Molecular Formula	C34H48N2O10S
Molecular Weight	676.82 g/mol
Synonyms	Atropine Sulphate; Atropini Sulfas; DL-Hyoscyamine Sulfate; (±)-Hyoscyamine Sulfate; 8-Methyl-8-azabicyclo[3.2.1]oct-3-yl 3-hydroxy-2-phenylpropanoate sulfate (1:1); Tropine tropate sulfate; Endotropin; Atropisol Sulfate
EINECS	200-235-9

Quality Control

Our Atropine Sulfate is manufactured under strict quality management systems. Each batch is tested to meet stringent specifications, which may align with pharmacopeial standards such as USP, EP, or BP, depending on the grade supplied. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to ensure traceability and regulatory compliance for our global B2B clients.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White or almost white, crystalline powder
Identification (IR)	Conforms
Identification (TLC)	Conforms
Assay (HPLC)	98.0% - 102.0% (on dried basis)
Loss on Drying	≤ 1.0%
Sulfated Ash	≤ 0.1%
Specific Rotation	-0.30° to +0.30°
Related Substances (HPLC)	Total impurities ≤ 1.0% Any individual impurity ≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.