Description

Pyridostigmine CAS NO 155-97-5 is a reversible cholinesterase inhibitor belonging to the carbamate class of compounds. Its primary value lies in its ability to enhance cholinergic transmission, making it a critical active pharmaceutical ingredient (API) for therapeutic applications. This product is essential for manufacturers in the pharmaceutical industry, particularly for the production of medications targeting neuromuscular conditions.

Application

• Pharmaceutical API: Primary use as the active ingredient in medications for the treatment of myasthenia gravis, a chronic autoimmune neuromuscular disease.
• Military & Prophylactic Use: Key component in nerve agent pretreatment regimens (e.g., against Soman) to increase survival rates following exposure.
• Post-Operative Care: Used to reverse the effects of non-depolarizing neuromuscular blocking agents administered during surgery.
• Research & Development: Serves as a reference standard and a crucial tool compound in pharmacological and neurological research studies.
• Formulation Development: Utilized in the development of various dosage forms, including tablets and extended-release formulations.

Basic Information

Product Name	Pyridostigmine
CAS No.	155-97-5
Molecular Formula	C9H13N2O2
Molecular Weight	181.21 g/mol
Synonyms	Pyridostigmine Bromide (common salt form); 3-[[(Dimethylamino)carbonyl]oxy]-1-methylpyridinium Bromide; Mestinon®; Regonol®; Kalymin®; 1-Methyl-3-hydroxy-pyridinium bromide dimethylcarbamate; EINECS 205-854-7

Quality Control

Our Pyridostigmine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure it meets high-purity standards suitable for pharmaceutical applications. A detailed Certificate of Analysis (COA), confirming identity, purity, and impurity profiles via methods such as HPLC, is provided with every shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area. Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption. Recommended long-term storage temperature is between 2°C and 8°C (refrigerated).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0% Any individual impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.