Description

Galantamine Hydrobromide is a high-purity alkaloid salt derived from natural sources and synthesized for pharmaceutical applications. It serves as a potent and selective acetylcholinesterase inhibitor, making it a critical active pharmaceutical ingredient (API) for cognitive support. This compound is essential for manufacturers in the pharmaceutical industry developing treatments for neurological conditions. We supply it with a focus on stringent quality control and reliable global supply chains.

Application

• Pharmaceutical API: Primary use as the active ingredient in prescription medications for the treatment of mild to moderate Alzheimer's disease and other memory-related cognitive disorders.
• Neurological Research: A key reference standard and biochemical tool in neuroscience research for studying cholinergic systems, enzyme inhibition, and cognitive function.
• Finished Dosage Formulation: Used in the development and production of various oral solid dosage forms, including tablets and capsules.
• Veterinary Medicine: Investigated for potential applications in cognitive dysfunction syndrome (CDS) in aging pets.
• Reference Standard: Serves as a high-purity certified reference material (CRM) for quality control laboratories in pharmacopeial testing (USP, EP).

Basic Information

Product Name	Galantamine Hydrobromide
CAS No.	1953-04-4
Molecular Formula	C17H21NO3 • HBr
Molecular Weight	368.27 g/mol
Synonyms	Galantamine HBr; Galanthamine Hydrobromide; Lycoramine; Jilkon; Nivalin; Reminyl (as API); (4aS,6R,8aS)-4a,5,9,10,11,12-Hexahydro-3-methoxy-11-methyl-6H-benzofuro[3a,3,2-ef][2]benzazepin-6-ol hydrobromide
EINECS	217-796-2

Quality Control

Our Galantamine Hydrobromide is manufactured and tested to meet high-grade pharmaceutical standards. Quality assurance protocols are designed to ensure identity, purity, strength, and composition, referencing pharmacopeial monographs such as USP and EP. A comprehensive Certificate of Analysis (COA) is provided with each batch, detailing results for assay, related substances, residual solvents, and other critical parameters.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference standard
Identification (HPLC)	Retention time corresponds to reference
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Related Substances (HPLC)	Total impurities ≤ 1.0% Any single impurity ≤ 0.5%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Complies with ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.