Description

4-Fluoro-2-(Methylsulfonyl)Benzoic Acid is a high-purity, multifunctional benzoic acid derivative distinguished by its fluorinated and sulfonyl substituents. This compound serves as a critical pharmaceutical intermediate and versatile building block in advanced organic synthesis, enabling the development of novel active ingredients. It is primarily utilized by R&D chemists and process development teams in the pharmaceutical, agrochemical, and specialty chemical industries seeking to introduce specific functional groups into complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of new drug candidates, particularly in medicinal chemistry programs targeting kinase inhibitors and other small molecule therapeutics.
• Agrochemical Synthesis: Used as a precursor in the manufacture of advanced herbicides and pesticides, where the fluorine atom and sulfone group contribute to biological activity and environmental stability.
• Ligand and Catalyst Development: Serves as a building block for creating novel ligands and organocatalysts used in asymmetric synthesis and cross-coupling reactions.
• Material Science Research: Employed in the synthesis of functional monomers and polymers, such as polyimides or liquid crystals, where its unique structure can impart specific thermal or optical properties.
• Chemical Biology Probes: Useful for synthesizing labeled compounds or probes for studying biological pathways and protein interactions.

Basic Information

Product Name	4-Fluoro-2-(Methylsulfonyl)Benzoic Acid
CAS No.	943224-29-1
Molecular Formula	C8H7FO4S
Molecular Weight	218.20 g/mol
Synonyms	2-(Methylsulfonyl)-4-fluorobenzoic Acid; 4-Fluoro-2-methanesulfonylbenzoic Acid; Benzoic acid, 4-fluoro-2-(methylsulfonyl)-; 4-Fluoro-2-methylsulfonylbenzoic Acid; 4-Fluoro-2-(methanesulfonyl)benzoic Acid; 943224-29-1; 4-Fluoro-2-(methylsulfonyl)benzoic acid
EINECS	Contact for details

Quality Control

Our 4-Fluoro-2-(Methylsulfonyl)Benzoic Acid is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high purity and consistent identity. We provide detailed Certificates of Analysis (COA) with each shipment, documenting all critical quality attributes. Our production adheres to cGMP principles where applicable, supporting its use in regulated research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); ensure the container is kept tightly sealed to prevent degradation from atmospheric moisture. Keep away from incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥98.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm
Related Substances (HPLC)	Total impurities ≤2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.