Description

4-[(2-Fluorophenoxy)Methyl]Benzoic Acid CAS NO 943114-74-7 is a high-purity fluorinated aromatic building block of significant interest in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of active pharmaceutical ingredients (APIs) and specialty agrochemicals, where the introduction of the fluorophenoxy moiety can dramatically alter biological activity and metabolic stability. It is primarily needed by research and development chemists, process development scientists, and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors seeking to incorporate this specific structural motif into novel molecules.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of novel drug candidates, particularly in therapeutic areas targeting the central nervous system, inflammation, and oncology.
• Agrochemical Synthesis: Used in the research and production of next-generation herbicides, fungicides, and insecticides, where the fluorine atom enhances lipophilicity and target binding.
• Liquid Crystal & OLED Materials: Serves as a precursor in the manufacture of fluorinated components for electronic display technologies and organic light-emitting diodes (OLEDs).
• Polymer Modification: Employed to introduce fluorinated aromatic groups into polymer chains, thereby improving chemical resistance, thermal stability, and surface properties of specialty plastics and coatings.
• Chemical Research & Development: A valuable reagent for academic and industrial R&D focused on exploring structure-activity relationships (SAR) in medicinal and materials chemistry.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for use in client-specific synthesis projects requiring this precise chemical scaffold.

Basic Information

Product Name	4-[(2-Fluorophenoxy)Methyl]Benzoic Acid
CAS No.	943114-74-7
Molecular Formula	C14H11FO3
Molecular Weight	246.24 g/mol
Synonyms	4-[(2-Fluorophenoxy)methyl]benzoic acid; Benzoic acid, 4-[(2-fluorophenoxy)methyl]-; 2-Fluoro-α-(4-carboxyphenoxy)toluene; 4-[(2-Fluorophenoxy)methyl]benzoic acid; (4-Carboxyphenyl)(2-fluorophenyl)methyl ether; p-[(2-Fluorophenoxy)methyl]benzoic acid; 4-(2-Fluorophenoxymethyl)benzoic acid; 943114-74-7
EINECS	Contact for details

Quality Control

Our 4-[(2-Fluorophenoxy)Methyl]Benzoic Acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing to ensure it meets the high-purity standards required for sensitive synthetic applications. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided and available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials such as strong oxidizing agents, strong bases, and strong acids. The container should be kept tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.