Description

Amiselimod (MT-1303) Hydrochloride is a high-purity, small molecule pharmaceutical reference standard and active pharmaceutical ingredient (API) intermediate. This compound is a selective sphingosine-1-phosphate (S1P) receptor modulator, making it a critical component in advanced pharmaceutical research and development. It is primarily utilized by pharmaceutical companies, contract research organizations (CROs), and academic institutions engaged in the development of novel immunomodulatory and anti-inflammatory therapies.

Application

• Pharmaceutical Reference Standard: Used for analytical method development, validation, and quality control (QC) testing in regulatory submissions.
• Active Pharmaceutical Ingredient (API) Intermediate: Serves as a key building block in the synthesis of final drug substances targeting autoimmune diseases.
• Preclinical & Clinical Research: Essential for in-vitro and in-vivo studies investigating S1P receptor biology and therapeutic potential.
• Drug Discovery & Development: A vital tool for medicinal chemists and pharmacologists in structure-activity relationship (SAR) studies.
• Impurity Identification & Characterization: Used as a marker to identify and quantify related substances in complex API matrices.

Basic Information

Product Name	Amiselimod (MT-1303) Hydrochloride
CAS No.	942398-84-7
Molecular Formula	C₂₃H₂₇ClN₂O₃
Molecular Weight	414.92 g/mol
Synonyms	MT-1303; MT1303; Amiselimod HCl; (R)-2-Amino-2-[4-(5-phenyl-1,2,4-oxadiazol-3-yl)benzyl]propan-1-ol hydrochloride; 2-Amino-2-[4-(5-phenyl-1,2,4-oxadiazol-3-yl)benzyl]propan-1-ol hydrochloride (R)-; BRN 19246966; S1P Receptor Modulator MT-1303
EINECS	Contact for details

Quality Control

Our Amiselimod (MT-1303) Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and residual solvent determination, to ensure it meets stringent specifications for pharmaceutical research. A detailed Certificate of Analysis (COA) with batch-specific data is provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry environment. For long-term storage, consider storing desiccated at 2-8°C.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥98.0%
Chiral Purity	≥99.0% ee
Water Content (KF)	≤0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Heavy Metals	<10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.