Description

Methyldeoxyspergualin is a potent synthetic analog of the natural product spergualin, characterized by its immunosuppressive and antitumor properties. This compound is of significant interest in pharmaceutical research and development due to its ability to inhibit key cellular processes. It is primarily utilized by researchers and manufacturers in the life sciences sector for advanced therapeutic applications and as a critical biochemical tool.

Application

• Immunosuppressive Agent Research: A key compound for studying and developing novel therapies for autoimmune diseases and organ transplant rejection.
• Oncology Research: Investigated for its antitumor activity and potential as a chemotherapeutic agent or adjuvant in cancer treatment studies.
• Biochemical Pathway Inhibition: Used as a specific inhibitor to study intracellular signaling pathways, particularly those involving heat shock protein 70 (Hsp70) and nuclear factor kappa B (NF-κB).
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in pharmaceutical analysis.
• Preclinical Drug Development: Employed in in vitro and in vivo studies to evaluate pharmacokinetics, efficacy, and safety profiles.

Basic Information

Product Name	Methyldeoxyspergualin
CAS No.	114760-35-9
Molecular Formula	C17H37N7O3
Molecular Weight	387.52 g/mol
Synonyms	15-Deoxyspergualin 17-methyl ether; Methyl-15-deoxyspergualin; DSG-ME; (-)-15-Deoxyspergualin 17-methyl ether; (S)-1-Amino-19-guanidino-11-hydroxy-4,9,12-triazanonadecane-10,13-dione 17-methyl ether; Gusperimus 17-methyl ether; N1-[N2-(3-Aminopropyl)-N2-methyl-L-α-glutaminyl]-1-guanyl-1,7-diaminoheptane
EINECS	Contact for details

Quality Control

Our Methyldeoxyspergualin is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research applications. Each lot undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.