Description

4-Fluoro-2-Nitro-Benzoic Acid tert-Butyl Ester is a high-purity, versatile chemical intermediate essential for advanced organic synthesis. Its molecular structure, featuring both a nitro and a fluoro substituent on an aromatic ring protected by a tert-butyl ester, makes it a critical building block for constructing complex molecules. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for developing new active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in medicinal chemistry research for fluorinated compounds.
• Agrochemical Synthesis: Used in the development of advanced herbicides, pesticides, and fungicides, where the fluorine atom enhances biological activity and stability.
• Organic Synthesis Building Block: Serves as a protected benzoic acid derivative in multi-step synthetic routes, including peptide coupling and cross-coupling reactions.
• Material Science Research: Employed in the creation of specialty polymers, liquid crystals, and advanced organic materials requiring specific fluorinated aromatic units.
• Chemical Research & Development: A valuable reagent for academic and industrial R&D labs exploring new synthetic methodologies and fluorine chemistry.

Basic Information

Product Name	4-Fluoro-2-Nitro-Benzoic Acid tert-Butyl Ester
CAS No.	942271-60-5
Molecular Formula	C11H12FNO4
Molecular Weight	241.22 g/mol
Synonyms	tert-Butyl 4-fluoro-2-nitrobenzoate; 4-Fluoro-2-nitrobenzoic acid tert-butyl ester; Benzoic acid, 4-fluoro-2-nitro-, 1,1-dimethylethyl ester; 1,1-Dimethylethyl 4-fluoro-2-nitrobenzoate; 2-Nitro-4-fluorobenzoic acid tert-butyl ester; tert-Butyl 2-nitro-4-fluorobenzoate; 942271-60-5; 4-Fluoro-2-nitro-benzoic acid tert-butyl ester
EINECS	Contact for details

Quality Control

Our 4-Fluoro-2-Nitro-Benzoic Acid tert-Butyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high chemical purity and identity confirmation. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to guarantee consistency and support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, the container should be opaque or stored in darkness.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.