Description

2,3-Difluoro-5-Nitrobenzoic Acid is a high-purity, multi-functional aromatic building block of significant importance in advanced organic synthesis. Its value lies in the strategic positioning of its nitro and carboxylic acid functional groups, which can be selectively modified, making it a versatile precursor for complex molecular architectures. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, where it is used to create novel active ingredients and specialty intermediates.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in the development of fluorinated drug candidates where the difluoro substitution can enhance metabolic stability and bioavailability.
• Agrochemical Synthesis: Serves as a critical precursor in the research and production of advanced herbicides, pesticides, and fungicides, leveraging the nitro group for further functionalization.
• Ligand and Catalyst Development: Used in the preparation of specialized ligands for metal-catalyzed cross-coupling reactions, a cornerstone of modern synthetic chemistry.
• Material Science Research: Employed in the synthesis of functionalized monomers and polymers, contributing to the development of advanced materials with specific electronic or optical properties.
• Chemical Biology Probes: Acts as a starting material for creating fluorinated probes and tags used in biochemical assays and diagnostic research.

Basic Information

Product Name	2,3-Difluoro-5-Nitrobenzoic Acid
CAS No.	942035-31-6
Molecular Formula	C7H3F2NO4
Molecular Weight	203.10 g/mol
Synonyms	5-Nitro-2,3-difluorobenzoic Acid; Benzoic acid, 2,3-difluoro-5-nitro-; 2,3-Difluoro-5-nitro-benzoic acid; 942035-31-6; 2,3-Difluoro-5-nitrobenzoic acid (ACI); 2,3-Difluoro-5-nitrobenzoic acid, 97%
EINECS	Contact for details

Quality Control

Every batch of 2,3-Difluoro-5-Nitrobenzoic Acid is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the product meets the high-purity requirements for research and scale-up applications. A detailed Certificate of Analysis (COA) confirming identity, purity (typically ≥97% by HPLC), and impurity profile is supplied with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong acids and incompatible materials. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.