Description

T-Butyl 4-Chloro-2-Fluorobenzoate is a high-purity, synthetically valuable benzoate ester derivative, serving as a critical building block in advanced organic synthesis. Its molecular structure, featuring both chloro and fluoro substituents, makes it an essential intermediate for constructing complex molecules with tailored electronic and steric properties. This compound is primarily utilized by research institutions and industrial R&D departments in the pharmaceutical and agrochemical sectors for developing new active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and metabolic diseases.
• Agrochemical Synthesis: Employed in the development of next-generation herbicides and fungicides, where the fluorine atom enhances biological activity and environmental stability.
• Liquid Crystal & OLED Materials: Used as a building block for creating advanced organic electronic materials, including liquid crystal displays (LCDs) and organic light-emitting diodes (OLEDs).
• Polymer Chemistry: Acts as a monomer or modifier in the production of specialty polymers with specific thermal and chemical resistance properties.
• Chemical Research & Development: Serves as a versatile reagent in academic and industrial labs for methodology development and exploring new chemical spaces.
• Custom Synthesis & Contract Manufacturing: A fundamental starting material for custom synthesis projects requiring functionalized aromatic compounds.

Basic Information

Product Name	T-Butyl 4-Chloro-2-Fluorobenzoate
CAS No.	941294-14-0
Molecular Formula	C11H12ClFO2
Molecular Weight	230.66 g/mol
Synonyms	4-Chloro-2-fluorobenzoic acid tert-butyl ester; tert-Butyl 4-chloro-2-fluorobenzoate; 2-Fluoro-4-chlorobenzoic acid tert-butyl ester; Benzoic acid, 4-chloro-2-fluoro-, 1,1-dimethylethyl ester; t-Butyl 4-chloro-2-fluorobenzoate; 1,1-Dimethylethyl 4-chloro-2-fluorobenzoate; TB4C2FB
EINECS	Contact for details

Quality Control

Our T-Butyl 4-Chloro-2-Fluorobenzoate is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with agreed specifications. Our quality commitment supports applications requiring GMP-grade intermediates and materials for regulatory filings.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong acids and incompatible materials such as strong bases and oxidizing agents. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (GC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.