Description

3-Fluoro-4-Nitrophenylboronic Acid, Pinacol Ester is a high-purity, synthetically valuable organoboron building block. This compound is critical for facilitating Suzuki-Miyaura cross-coupling reactions, a cornerstone methodology in modern pharmaceutical and agrochemical research. It is primarily utilized by R&D chemists and process development scientists in the life sciences sector for constructing complex molecular architectures containing fluorinated aromatic systems.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, particularly those requiring a fluorinated aromatic moiety for metabolic stability or binding affinity.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and insecticides where the 3-fluoro-4-nitrophenyl group imparts specific biological activity.
• Material Science Precursor: Serves as a building block for creating advanced organic electronic materials, such as OLEDs or semiconductors, via cross-coupling polymerization.
• Ligand and Catalyst Development: Employed in the synthesis of specialized ligands or organometallic catalysts for asymmetric synthesis and other catalytic processes.
• Chemical Biology Probes: Useful for constructing fluorescent tags, bioconjugation handles, or other molecular probes for biological imaging and diagnostic applications.
• Custom Synthesis and Contract Manufacturing: A vital reagent for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the global pharmaceutical and biotechnology industries.

Basic Information

Product Name	3-Fluoro-4-Nitrophenylboronic Acid, Pinacol Ester
CAS No.	939968-60-2
Molecular Formula	C₁₂H₁₅BFNO₄
Molecular Weight	267.06 g/mol
Synonyms	4-Nitro-3-fluorophenylboronic acid pinacol ester; (3-Fluoro-4-nitrophenyl)boronic acid pinacol ester; 2-(3-Fluoro-4-nitrophenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 3-Fluoro-4-nitrophenyl-Bpin; B-(3-Fluoro-4-nitrophenyl)pinacolborane; 939968-60-2; 3-Fluoro-4-nitrobenzeneboronic acid pinacol ester
EINECS	Contact for details

Quality Control

Every batch of our 3-Fluoro-4-Nitrophenylboronic Acid, Pinacol Ester undergoes rigorous analytical testing to ensure it meets the high-purity standards required for sensitive coupling reactions. Our quality assurance protocols are designed to guarantee batch-to-batch consistency and reliability. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and light-sensitive (store away from light); therefore, containers must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥97.0% (Area %)
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.