Description

(S)-[Trimethylsiloxy(Diphenyl)Methyl]Pyrrolidine is a high-value, chiral organosilicon compound primarily used as a versatile catalyst and chiral auxiliary in advanced organic synthesis. Its significance lies in enabling highly stereoselective transformations, which are critical for producing enantiomerically pure intermediates in pharmaceutical and fine chemical manufacturing. This product is essential for R&D chemists and process development scientists working in asymmetric synthesis, particularly for the production of active pharmaceutical ingredients (APIs), agrochemicals, and specialty materials.

Application

• As a chiral catalyst or ligand in asymmetric carbon-carbon and carbon-heteroatom bond-forming reactions.
• As a chiral auxiliary for the stereocontrolled synthesis of complex organic molecules and natural products.
• In the research and development of enantiomerically pure pharmaceutical intermediates, especially for central nervous system (CNS) and cardiovascular drugs.
• For the synthesis of advanced agrochemicals requiring specific stereochemistry for optimal biological activity.
• In academic and industrial R&D focused on novel methodologies in organocatalysis and silicon chemistry.
• For the production of specialty fine chemicals and flavors & fragrances where chirality is a key factor.

Basic Information

Product Name	(S)-[Trimethylsiloxy(Diphenyl)Methyl]Pyrrolidine
CAS No.	937202-23-8
Molecular Formula	C20H27NOSi
Molecular Weight	325.52 g/mol
Synonyms	(S)-(-)-2-(Diphenyltrimethylsilyloxymethyl)pyrrolidine; (S)-2-[(Diphenyl(trimethylsilyl)oxy)methyl]pyrrolidine; (S)-Diphenyl(trimethylsilyloxy)methylpyrrolidine; (S)-TMS-DPMP; (S)-α-(Diphenyl(trimethylsiloxy)methyl)pyrrolidine; (S)-N-[(Diphenyl(trimethylsilyl)oxy)methyl]pyrrolidine; Chiral Pyrrolidine Silyl Ether; (S)-DPMP-TMS
EINECS	Contact for details

Quality Control

Our (S)-[Trimethylsiloxy(Diphenyl)Methyl]Pyrrolidine is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high chemical purity. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing key parameters such as chiral purity (enantiomeric excess), chemical assay, and impurity profiles. We adhere to cGMP principles where applicable, and our quality systems are designed to meet the stringent requirements of pharmaceutical and advanced synthetic chemistry applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage and to prevent degradation upon repeated opening.

Specification

Item	Specification
Appearance	Colorless to pale yellow viscous liquid or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.