Description

3-Fluoro-5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Benzoic Acid is a high-purity, synthetically valuable boronic ester derivative. This compound serves as a critical building block in modern organic synthesis, particularly for cross-coupling reactions that form carbon-carbon bonds. It is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require precise and reliable intermediates for drug discovery and specialty chemical production.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel active pharmaceutical ingredients (APIs) and drug candidates.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides requiring fluorinated aromatic structures.
• Liquid Crystal & OLED Materials: Serves as a building block for creating fluorinated organic electronic materials used in displays and lighting.
• Polymer Chemistry: Incorporated into specialty polymers to modify thermal stability, chemical resistance, and optical properties.
• Chemical Research & Development: A versatile reagent for academic and industrial R&D labs exploring new synthetic methodologies and complex molecule construction.
• Fluorine Chemistry: Exploits the unique properties of the fluorine atom for creating compounds with enhanced metabolic stability and bioavailability.

Basic Information

Product Name	3-Fluoro-5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Benzoic Acid
CAS No.	936728-22-2
Molecular Formula	C13H16BFO4
Molecular Weight	266.08 g/mol
Synonyms	3-Fluoro-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzoic acid; 5-Carboxy-3-fluorophenylboronic acid pinacol ester; (3-Carboxy-5-fluorophenyl)boronic acid pinacol ester; 3-Fluoro-5-(pinacolatoboryl)benzoic acid; Benzoic acid, 3-fluoro-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-; 936728-22-2; 3-Fluoro-5-boronobenzoic acid pinacol ester
EINECS	Contact for details

Quality Control

Every batch of our 3-Fluoro-5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Benzoic Acid undergoes rigorous analytical testing to ensure it meets the high-purity standards required for sensitive synthetic applications. Our quality assurance protocols include HPLC, NMR, and MS to verify identity, purity, and the absence of critical impurities. A comprehensive Certificate of Analysis (COA) is provided with each shipment, detailing all relevant specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0%
Water Content (KF)	≤0.5%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.