Description

5-Ipf2α-Vi-D11 is a deuterated analog of the isoprostane biomarker 5-iPF2α-VI, designed for advanced analytical and research applications. This compound is critical for use as a high-purity internal standard in mass spectrometry, enabling precise quantification of oxidative stress markers in biological samples. It is primarily utilized by researchers and quality control laboratories in the pharmaceutical, biotechnology, and clinical diagnostics sectors.

Application

• Internal Standard for LC-MS/MS: Used for the accurate quantification of isoprostanes in plasma, urine, and tissue samples in clinical research.
• Biomarker Research: Essential in studies investigating oxidative stress related to cardiovascular disease, neurodegenerative disorders, and metabolic conditions.
• Pharmaceutical Development: Employed in drug discovery and development programs targeting pathways involving lipid peroxidation and inflammation.
• Diagnostic Assay Calibration: Serves as a reference standard in the development and validation of diagnostic kits for oxidative stress assessment.
• Metabolomics and Lipidomics: A key analytical standard in high-throughput profiling studies to understand disease mechanisms.
• Toxicology Studies: Applied in research evaluating the impact of toxins or environmental stressors on lipid peroxidation levels.

Basic Information

Product Name	5-Ipf2α-Vi-D11
CAS No.	936565-17-2
Molecular Formula	C20H27D11O5
Molecular Weight	~369.6 g/mol
Synonyms	5-iPF2α-VI-d11; 8-iso-15(R)-Prostaglandin F2α-d11; 8-iso-PGF2α-VI-d11; 15(R)-8-iso-Prostaglandin F2α-d11; 5-iPF2α-VI Internal Standard; Deuterated 8-iso-PGF2α; 8-epi-PGF2α-d11; Isoprostane F2α-VI-d11
EINECS	Contact for details

Quality Control

Every batch of 5-Ipf2α-Vi-D11 is manufactured under strict quality management systems and undergoes comprehensive analytical characterization. We guarantee high chemical and isotopic purity, confirmed by NMR, HPLC, and mass spectrometry. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting purity, isotopic enrichment, and solvent content to ensure it meets the rigorous standards required for analytical research.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability. For long-term storage, keep desiccated.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (NMR)	Conforms to structure
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Enrichment	≥ 98 atom % D
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.