Description

4-Fluorosulfonyl-3-Methoxy-Benzoic Acid is a high-purity, multi-functional aromatic building block of significant interest in advanced organic synthesis. Its unique molecular architecture, featuring both a reactive fluorosulfonyl group and a carboxylic acid moiety, makes it a critical intermediate for constructing complex molecules with tailored properties. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for applications in medicinal chemistry and crop protection science.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for sulfonamide-based drug candidates targeting various therapeutic areas.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, where the fluorosulfonyl group can enhance biological activity and environmental profile.
• Material Science Research: Acts as a monomer or functionalization agent in the creation of specialty polymers, coatings, and advanced materials with specific surface properties.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes and labeling reagents for studying biological processes and enzyme activity.
• Ligand and Catalyst Development: Useful for constructing sophisticated chelating ligands and organocatalysts used in asymmetric synthesis and metal complexation.

Basic Information

Product Name	4-Fluorosulfonyl-3-Methoxy-Benzoic Acid
CAS No.	935534-26-2
Molecular Formula	C8H7FO5S
Molecular Weight	234.20 g/mol
Synonyms	3-Methoxy-4-(fluorosulfonyl)benzoic acid; Benzoic acid, 4-(fluorosulfonyl)-3-methoxy-; 4-(Fluorosulfonyl)-3-methoxybenzoic acid; 4-Fluorosulfonyl-3-methoxybenzoic acid; 3-Methoxy-4-fluorosulfonylbenzoic acid
EINECS	Contact for details

Quality Control

Our 4-Fluorosulfonyl-3-Methoxy-Benzoic Acid is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot is subjected to comprehensive analytical testing, including HPLC for assay and impurity profiling, NMR for structural confirmation, and Karl Fischer titration for moisture content. A Certificate of Analysis (COA) detailing all specifications and test results is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Single Unknown Impurity	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.