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2,3-Difluoro-5-Methylphenylboronic Acid CAS NO 934247-79-7


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CAS No.:934247-79-7

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

2,3-Difluoro-5-Methylphenylboronic Acid is a high-purity organoboron compound serving as a critical building block in modern synthetic chemistry. Its value lies in enabling precise carbon-carbon bond formation via Suzuki-Miyaura cross-coupling reactions, a cornerstone for constructing complex molecular architectures. This boronic acid is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors, particularly for developing novel active ingredients and functional organic molecules. We supply this material with a focus on batch-to-batch consistency and reliable global logistics to support your R&D and production timelines.

Application

  • Pharmaceutical Intermediate: A key synthon for constructing fluorinated drug candidates, leveraging the fluorine atoms to modulate bioavailability, metabolic stability, and binding affinity.
  • Agrochemical Synthesis: Used in the development of new-generation herbicides, fungicides, and insecticides where the difluoromethylphenyl moiety imparts desired biological activity.
  • Material Science Research: Employed in the synthesis of organic electronic materials, such as ligands for OLEDs or building blocks for conductive polymers.
  • Cross-Coupling Reactions: Primarily utilized in palladium-catalyzed Suzuki-Miyaura couplings to create biaryl and heterobiaryl structures central to many fine chemicals.
  • Chemical Biology Probes: Serves as a precursor for labeling reagents or probe molecules used in diagnostic and biochemical research.
  • Custom Synthesis: Provides a versatile starting point for contract research organizations (CROs) and custom synthesis houses serving diverse client projects.

Basic Information

Product Name 2,3-Difluoro-5-Methylphenylboronic Acid
CAS No. 934247-79-7
Molecular Formula C7H7BF2O2
Molecular Weight 171.94 g/mol
Synonyms (2,3-Difluoro-5-methylphenyl)boronic acid; 5-Methyl-2,3-difluorophenylboronic acid; 2,3-Difluoro-5-methylbenzeneboronic acid; Boronic acid, B-(2,3-difluoro-5-methylphenyl)-; 934247-79-7; 2,3-Difluoro-5-methylphenyl-B(OH)2
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Quality Control

Every batch of 2,3-Difluoro-5-Methylphenylboronic Acid is manufactured and tested under a strict quality management system. We employ advanced analytical techniques including HPLC, NMR, and mass spectrometry to verify identity, purity, and to control critical impurities. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with each shipment to ensure full traceability and compliance with your project specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic nature, the container should be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and maintain product integrity. Recommended long-term storage temperature is 2-8°C.

Specification

Item Specification
Appearance White to off-white crystalline powder
Identification (IR) Conforms to structure
Identification (NMR) Conforms to structure
Purity (HPLC) ≥97.0% (Area %)
Water Content (KF) ≤1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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