Description

Bis(Di-tert-Butyl)-4-Dimethylaminophenylphosphine is a specialized organophosphorus ligand featuring a sterically hindered, electron-rich structure. This compound is valued for its ability to modulate catalytic activity and selectivity in challenging cross-coupling and other transition metal-catalyzed reactions. It is primarily utilized by researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials sectors for developing novel synthetic pathways and optimizing existing processes.

Application

• As a ligand in palladium-catalyzed cross-coupling reactions, such as Suzuki-Miyaura, Buchwald-Hartwig amination, and C-N bond formation.
• For catalyst development in fine chemical and pharmaceutical intermediate synthesis, enabling more efficient and selective transformations.
• In academic and industrial R&D for exploring new catalytic systems and reaction mechanisms.
• As a precursor or additive in materials science, particularly in the synthesis of specialized polymers or metal-organic frameworks (MOFs).
• For studying steric and electronic effects of phosphine ligands on metal center reactivity.

Basic Information

Product Name	Bis(Di-tert-Butyl)-4-Dimethylaminophenylphosphine
CAS No.	932710-63-9
Molecular Formula	C20H36NP
Molecular Weight	321.48 g/mol
Synonyms	4-(Dimethylamino)phenylbis(3,3-dimethylbutyl)phosphine; (4-(Dimethylamino)phenyl)bis(3,3-dimethylbutyl)phosphine; Di-tert-butyl(4-dimethylaminophenyl)phosphine; DTBP-DMAPhosphine; Ligand DTBP-DMAP; Tris(3,3-dimethylbutyl)phosphine derivative; P(4-NMe2C6H4)(C(CH3)3)2
EINECS	Contact for details

Quality Control

Our Bis(Di-tert-Butyl)-4-Dimethylaminophenylphosphine is produced and handled under strict quality protocols to ensure batch-to-batch consistency and high purity. Each lot is characterized using advanced analytical techniques including NMR, HPLC, and elemental analysis. A Certificate of Analysis (COA) detailing purity, identity, and relevant specifications is provided with every shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at controlled room temperature (15-25°C) in a cool, dry, and well-ventilated place. Due to its sensitivity to oxidation, containers should be kept sealed and only opened in an inert environment.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.