Description

5-Fluoro-6-Methylnicotinic Acid is a high-value fluorinated pyridine derivative, serving as a critical building block in advanced organic synthesis. Its unique structure, featuring both fluorine and methyl substituents on the nicotinic acid core, makes it indispensable for creating novel compounds with tailored properties. This intermediate is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for the development of new active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of novel active pharmaceutical ingredients (APIs), particularly in medicinal chemistry programs targeting CNS and metabolic diseases.
• Agrochemical Synthesis: Used in the creation of advanced herbicides and pesticides, where the fluorine atom enhances biological activity and environmental stability.
• Ligand and Catalyst Development: Serves as a precursor for synthesizing specialized ligands used in catalytic processes and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the development of organic electronic materials and functional polymers due to its electron-withdrawing characteristics.
• Chemical Biology Probes: Utilized to create fluorinated analogs of natural products for metabolic pathway studies and biochemical research.

Basic Information

Product Name	5-Fluoro-6-Methylnicotinic Acid
CAS No.	932705-78-7
Molecular Formula	C7H6FNO2
Molecular Weight	155.13 g/mol
Synonyms	5-Fluoro-6-methylpyridine-3-carboxylic acid; 3-Pyridinecarboxylic acid, 5-fluoro-6-methyl-; 6-Methyl-5-fluoronicotinic acid; 5-Fluoro-6-methyl-3-pyridinecarboxylic acid; 5-Fluoro-6-methylnicotinate; 932705-78-7 (CAS); 5-Fluoro-6-methyl-3-carboxypyridine
EINECS	Contact for details

Quality Control

Our 5-Fluoro-6-Methylnicotinic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity verification and NMR/IR for structural confirmation, to ensure it meets the stringent requirements for advanced synthetic applications. A detailed Certificate of Analysis (COA) is provided with every shipment, guaranteeing traceability and consistent high purity.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, open flames, and incompatible materials. The compound is light-sensitive and should be handled accordingly to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.