Description

Methyl 2-Amino-5-Fluoro-4-Methylbenzoate is a high-purity fluorinated benzoate derivative, serving as a critical building block in advanced organic synthesis. Its value lies in its multifunctional structure, incorporating both an amino group and a fluorine atom, which are essential for modulating the biological activity and physicochemical properties of target molecules. This compound is primarily required by pharmaceutical R&D and fine chemical manufacturers for the development of active pharmaceutical ingredients (APIs), agrochemicals, and specialty materials.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of novel drug candidates, particularly in oncology and central nervous system (CNS) therapeutic areas.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides and pesticides, where the fluorine atom enhances efficacy and environmental stability.
• Liquid Crystal & OLED Materials: Serves as a precursor for fluorinated aromatic compounds used in electronic display technologies.
• Dye & Pigment Manufacturing: Acts as an intermediate for creating specialized fluorinated colorants with improved lightfastness and chromatic properties.
• Chemical Research & Development: Employed in academic and industrial labs for exploring new fluorination chemistry and constructing complex molecular architectures.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs for the scale-up and production of client-specific target molecules.

Basic Information

Product Name	Methyl 2-Amino-5-Fluoro-4-Methylbenzoate
CAS No.	929214-84-6
Molecular Formula	C9H10FNO2
Molecular Weight	183.18 g/mol
Synonyms	2-Amino-5-fluoro-4-methylbenzoic acid methyl ester; Methyl 5-fluoro-2-amino-p-toluate; Benzoic acid, 2-amino-5-fluoro-4-methyl-, methyl ester; 5-Fluoro-2-amino-4-methylbenzoic acid methyl ester; Methyl 2-amino-5-fluoro-4-methylbenzenecarboxylate; 929214-84-6; Methyl 5-fluoro-2-amino-4-methylbenzoate
EINECS	Contact for details

Quality Control

Our Methyl 2-Amino-5-Fluoro-4-Methylbenzoate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment aligns with cGMP principles where applicable, ensuring reliability for your most demanding synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥98.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤10 ppm
Related Substances (HPLC)	Individual impurity ≤0.5%; Total impurities ≤1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.