Description

2-Fluoro-4-[2-(Trifluoromethoxy)Phenyl]Benzoic Acid is a high-value, multi-functional fluorinated aromatic building block essential for advanced organic synthesis. Its unique structure, featuring both fluorine and trifluoromethoxy substituents, makes it a critical intermediate for developing novel compounds with tailored properties. This product is primarily targeted at research and development teams in the pharmaceutical and agrochemical industries, where it is used to create new active ingredients with potential applications in drug discovery and crop protection.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in medicinal chemistry programs targeting CNS disorders, inflammation, and metabolic diseases.
• Agrochemical Research: Used in the development of next-generation herbicides, fungicides, and insecticides, where the fluorine and trifluoromethoxy groups enhance biological activity and environmental stability.
• Liquid Crystal & OLED Material Synthesis: Serves as a precursor for advanced electronic materials, contributing to the molecular design of components for displays and organic light-emitting diodes.
• Polymer Modification: Employed to introduce fluorinated aromatic units into polymer backbones, improving chemical resistance, thermal stability, and surface properties of specialty polymers.
• Chemical Biology & Probe Development: Utilized as a scaffold for creating fluorescent probes or affinity labels to study biological processes and protein-ligand interactions.
• Custom Synthesis & Contract Manufacturing: Supplied to fine chemical manufacturers and CDMOs for use in custom synthesis projects and scale-up campaigns for clients.

Basic Information

Product Name	2-Fluoro-4-[2-(Trifluoromethoxy)Phenyl]Benzoic Acid
CAS No.	926234-72-2
Molecular Formula	C14H8F4O3
Molecular Weight	300.21 g/mol
Synonyms	2-Fluoro-4-[2-(trifluoromethoxy)phenyl]benzoic acid; 4-[2-(Trifluoromethoxy)phenyl]-2-fluorobenzoic acid; Benzoic acid, 2-fluoro-4-[2-(trifluoromethoxy)phenyl]-; 2-Fluoro-4-(2-trifluoromethoxyphenyl)benzoic acid; 926234-72-2; 2-Fluoro-4-(α,α,α-trifluoro-o-tolyloxy)benzoic acid (obsolete); [2-(Trifluoromethoxy)phenyl]-(2-fluoro-4-carboxyphenyl) (alternative); F-TFM-BA (abbreviation)
EINECS	Contact for details

Quality Control

Our 2-Fluoro-4-[2-(Trifluoromethoxy)Phenyl]Benzoic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure it meets the high standards required for research and development applications. Certificates of Analysis (COA) detailing all specifications are available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong acids and organic solvents. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.