Description

Benzoic Acid, 2-Fluoro-6-Iodo-, Ethyl Ester is a high-purity, halogenated aromatic ester building block of significant interest in advanced organic synthesis. This compound matters for its unique molecular architecture, which combines fluorine and iodine substituents to enable precise structural modifications and facilitate cross-coupling reactions. It is primarily needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the creation of novel active ingredients and complex intermediates.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, where the fluorine and iodine atoms can enhance biological activity and environmental stability.
• Material Science Precursor: Serves as a monomer or functionalization agent in the synthesis of specialty polymers and liquid crystals with tailored electronic or optical properties.
• Cross-Coupling Reactions: The iodine substituent makes it an excellent substrate for palladium-catalyzed reactions like Suzuki, Stille, and Sonogashira couplings, enabling rapid diversification of molecular scaffolds.
• Fluorine Chemistry Studies: Utilized as a model compound in research exploring the effects of fluorine substitution on aromatic systems and reaction pathways.
• Diagnostic Agent Development: Potential precursor for radiolabeling with iodine-123 or iodine-125 for use in medical imaging and diagnostic applications.

Basic Information

Product Name	Benzoic Acid, 2-Fluoro-6-Iodo-, Ethyl Ester
CAS No.	925215-01-6
Molecular Formula	C9H8FIO2
Molecular Weight	294.06 g/mol
Synonyms	Ethyl 2-Fluoro-6-iodobenzoate; 2-Fluoro-6-iodobenzoic Acid Ethyl Ester; Benzoic acid, 2-fluoro-6-iodo-, ethyl ester; Ethyl 2-fluoro-6-iodobenzoate; 925215-01-6; 2-Fluoro-6-iodo-benzoic acid ethyl ester; Ethyl (2-fluoro-6-iodophenyl)formate
EINECS	Contact for details

Quality Control

Our Benzoic Acid, 2-Fluoro-6-Iodo-, Ethyl Ester is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our commitment to quality supports your research and development needs with reliable, high-purity materials.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be kept in amber glass or opaque packaging during storage and handling.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Heavy Metals	< 10 ppm
Residual Solvents (GC)	Complies with ICH guidelines
Water Content (KF)	< 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.