Description

4-(Aminocarbonyl)-3,5-Difluorophenylboronic Acid is a high-purity boronic acid derivative featuring both difluoro and amide functional groups. This compound is a critical building block in modern synthetic chemistry, enabling the precise construction of complex molecules through cross-coupling reactions. It is primarily utilized by research scientists and process chemists in the pharmaceutical and agrochemical industries for the development of new active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel drug candidates, particularly in kinase inhibitor and oncology research.
• Agrochemical Synthesis: Used in the development of advanced herbicides and fungicides, leveraging the fluorine atoms for enhanced biological activity and metabolic stability.
• Material Science Research: Serves as a monomer or functionalization agent in the creation of organic electronic materials, sensors, and metal-organic frameworks (MOFs).
• Chemical Biology Probes: Employed in the synthesis of bioconjugates and activity-based probes for studying enzyme function and protein interactions.
• Process Chemistry & Scale-up: Provides a reliable, high-quality building block for the optimization and pilot-scale production of target molecules.

Basic Information

Product Name	4-(Aminocarbonyl)-3,5-Difluorophenylboronic Acid
CAS No.	924279-82-3
Molecular Formula	C7H6BF2NO3
Molecular Weight	200.94 g/mol
Synonyms	3,5-Difluoro-4-carbamoylphenylboronic Acid; 4-Carbamoyl-3,5-difluorophenylboronic Acid; (4-Carbamoyl-3,5-difluorophenyl)boronic Acid; 3,5-Difluoro-4-(aminocarbonyl)benzeneboronic Acid; 4-Borono-3,5-difluorobenzamide; CAS 924279-82-3
EINECS	Contact for details

Quality Control

Our 4-(Aminocarbonyl)-3,5-Difluorophenylboronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with detailed specifications are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere or in a dry environment to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.