Description

Centanafadine Hcl CAS NO 923981-14-0 is a high-purity pharmaceutical intermediate and research chemical, specifically the hydrochloride salt of Centanafadine. This compound is of significant interest for its role in the development of novel therapeutic agents targeting central nervous system disorders. It is primarily utilized by pharmaceutical R&D departments, contract research organizations (CROs), and fine chemical manufacturers engaged in advanced synthesis. Our supply is characterized by stringent quality control, ensuring reliability for critical development and production processes.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel triple monoamine reuptake inhibitors for clinical research.
• Neuropharmacology Research: Used in preclinical studies to investigate mechanisms related to depression, attention deficit hyperactivity disorder (ADHD), and other CNS conditions.
• Reference Standard: Serves as a certified reference material (CRM) for analytical method development, validation, and quality control in API manufacturing.
• Process Chemistry Development: Employed in route scouting, optimization, and scale-up activities within fine chemical and API production.
• Academic Research: Utilized in university and institutional labs for biochemical and pharmacological studies.

Basic Information

Product Name	Centanafadine Hydrochloride
CAS No.	923981-14-0
Molecular Formula	C18H21ClN2O2
Molecular Weight	332.82 g/mol
Synonyms	(1S,2S)-3-(Methylamino)-2-(naphthalen-1-yl)-1-phenylpropan-1-ol hydrochloride; (1S,2S)-3-(Methylamino)-1-phenyl-2-(1-naphthyl)propyl alcohol hydrochloride; Centanafadine HCl; NW-3509 hydrochloride; Triple Reuptake Inhibitor
EINECS	Contact for details

Quality Control

Every batch of Centanafadine HCl is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to support its use in regulated environments. Specifications typically meet or exceed >98.5% purity (HPLC), with full control of related substances and residual solvents. A detailed Certificate of Analysis (COA) is supplied with each shipment, documenting identity, purity, and other critical quality attributes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.5%
Related Substances (HPLC)	Total impurities ≤ 1.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.