Description

(+/-)-Enterolactone -13C3 is a stable isotope-labeled analog of the mammalian lignan enterolactone, where three carbon atoms are replaced with the carbon-13 isotope. This compound is essential for use as an internal standard in quantitative mass spectrometry, providing unparalleled accuracy and reliability in analytical measurements. It is a critical tool for researchers and quality control laboratories in the pharmaceutical, nutraceutical, and clinical diagnostics industries who require precise quantification of enterolactone and related metabolites in complex biological matrices.

Application

• Quantitative Mass Spectrometry (LC-MS/MS, GC-MS): Serves as a high-purity internal standard for the accurate quantification of enterolactone in pharmacokinetic and bioavailability studies.
• Clinical Research & Diagnostics: Enables precise measurement of enterolactone levels in human plasma, serum, and urine for studies on diet, phytoestrogens, and chronic disease biomarkers.
• Pharmaceutical Development: Used in drug metabolism and pharmacokinetic (DMPK) studies for compounds that interact with or are metabolized to enterolactone-related pathways.
• Nutraceutical & Food Science: Facilitates the accurate analysis of lignan content and bioavailability in functional foods, dietary supplements, and raw ingredients.
• Method Development & Validation: Critical for developing, optimizing, and validating robust analytical methods in compliance with guidelines like FDA 21 CFR Part 11 or ICH Q2(R1).
• Metabolomics & Biomarker Discovery: Supports high-throughput screening and precise profiling of lignan metabolites in large-scale metabolomic studies.

Basic Information

Product Name	(+/-)-Enterolactone -13C3
CAS No.	918502-72-4
Molecular Formula	C1813C3H20O4
Molecular Weight	~301.3 g/mol (Contact for exact value)
Synonyms	Enterolactone-13C3; 2,3-Bis(3-hydroxybenzyl)butane-1,4-diol-13C3; trans-2,3-Bis[(3-hydroxyphenyl)methyl]butane-1,4-diol-13C3; HMRlignan-13C3; ENL-13C3; Mammalian Lignan-13C3; (±)-Enterolactone-13C3
EINECS	Contact for details

Quality Control

Every batch of (+/-)-Enterolactone -13C3 is manufactured and analyzed under strict quality systems. We provide comprehensive Certificates of Analysis (COA) detailing isotopic purity (e.g., ≥99 atom % 13C), chemical purity (typically ≥98% by HPLC), and absence of interfering impurities. Our quality commitment ensures the reliability required for sensitive analytical applications, supporting compliance with GLP and ISO 17025 standards.

Storage

Preserve in a tightly closed container, protected from light. Store at 2-8°C in a dry, cool place. This product is hygroscopic (moisture-sensitive); ensure the container is sealed after each use to prevent degradation from atmospheric moisture. For long-term storage, consider storage under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity	≥ 99 atom % 13C
Chemical Purity (by NMR)	Conforms
Residual Solvents (GC)	Meets ICH guidelines
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.