Description

Letermovir is a potent antiviral agent specifically designed to inhibit the cytomegalovirus (CMV) terminase complex. This compound is of critical importance for the prevention and treatment of CMV infections, particularly in immunocompromised patient populations such as transplant recipients. It is primarily utilized by pharmaceutical manufacturers and research institutions engaged in antiviral drug development and production.

Application

• Active Pharmaceutical Ingredient (API) for the formulation of antiviral medications targeting cytomegalovirus (CMV).
• Research and Development of novel antiviral therapies and combination treatments.
• Reference Standard for analytical method development and quality control in pharmaceutical laboratories.
• Biochemical Research for studying the CMV replication cycle and terminase complex inhibition mechanisms.
• GMP Manufacturing for the commercial production of finished dosage forms under strict regulatory guidelines.

Basic Information

Product Name	Letermovir
CAS No.	917389-32-3
Molecular Formula	C₂₉H₂₈F₄N₄O₄
Molecular Weight	572.55 g/mol
Synonyms	Letermovir; AIC246; MK-8228; 4-Fluoro-2-({5-fluoro-3-[(2-{4-[(3-methyl-1,2,4-oxadiazol-5-yl)methoxy]phenyl}ethyl)amino]-2-oxopyridin-1(2H)-yl}methyl)benzonitrile; Prevymis (Brand Name)
EINECS	Contact for details

Quality Control

Our Letermovir is manufactured under strict quality systems to ensure it meets the rigorous standards required for pharmaceutical use. Each batch undergoes comprehensive analytical testing, including identity confirmation, purity assay, and impurity profiling via validated methods such as HPLC and NMR. A Certificate of Analysis (COA) detailing all specifications and results is provided with every shipment to guarantee traceability and compliance with cGMP and ICH guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Related Substances (HPLC)	Total impurities ≤2.0%
Any single unknown impurity	≤0.5%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.