Description

(S)-4-Benzyl-3-[(S)-3-(2-Bromo-4-Methoxyphenyl)-2-(4-Methoxyphenyl) Propanoyl]-2-Oxazolidinone is a high-purity, chiral oxazolidinone derivative that serves as a critical synthetic intermediate in advanced organic chemistry. Its value lies in its role as a versatile chiral auxiliary and building block for the stereoselective synthesis of complex, biologically active molecules. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly for constructing chiral centers in drug candidates and fine chemicals with high enantiomeric purity.

Application

• Pharmaceutical Intermediate: Key chiral building block for the synthesis of active pharmaceutical ingredients (APIs), especially in stereocontrolled reactions.
• Asymmetric Synthesis: Used as a chiral auxiliary in Evans aldol reactions and other enantioselective transformations to install defined stereochemistry.
• Medicinal Chemistry Research: Employed in the discovery and development of new therapeutic agents, particularly where bromo- and methoxy-substituted aromatic motifs are required.
• Agrochemical Synthesis: Intermediate in the production of advanced, chiral crop protection agents and pesticides.
• Fine Chemical Production: Used in the manufacture of specialty chemicals, flavors, and fragrances requiring high enantiopurity.
• Academic & Contract Research: A valuable reagent for methodology development and complex molecule synthesis in university and CRO laboratories.

Basic Information

Product Name	(S)-4-Benzyl-3-[(S)-3-(2-Bromo-4-Methoxyphenyl)-2-(4-Methoxyphenyl) Propanoyl]-2-Oxazolidinone
CAS No.	917379-10-3
Molecular Formula	C27H26BrNO5
Molecular Weight	524.41 g/mol
Synonyms	(4S)-4-Benzyl-3-[(2S)-3-(2-Bromo-4-methoxyphenyl)-2-(4-methoxyphenyl)propanoyl]-1,3-oxazolidin-2-one; (S)-4-Benzyl-3-[(S)-3-(2-Bromo-4-methoxyphenyl)-2-(4-methoxyphenyl)propionyl]-2-oxazolidinone; Evans Auxiliary Derivative; Bromo-dimethoxy Evans Auxiliary; Chiral Oxazolidinone Auxiliary 917379-10-3
EINECS	Contact for details

Quality Control

Every batch of our (S)-4-Benzyl-3-[(S)-3-(2-Bromo-4-Methoxyphenyl)-2-(4-Methoxyphenyl) Propanoyl]-2-Oxazolidinone is manufactured and tested under strict quality management systems. We ensure compliance with high-purity standards suitable for pharmaceutical R&D and fine chemical synthesis. Comprehensive analytical testing, including chiral HPLC, NMR, and mass spectrometry, is performed to verify identity, purity, and enantiomeric excess. Certificates of Analysis (COA) detailing all specifications are provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) when not in use to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.